Causes of death and selected standardized mortality ratios (SMR)* among 2950 males with hemophilia in six US states, 1993-1995
| Cause of death . | Number (%†) of persons (N = 236) . | SMR . | 95% CI . |
|---|---|---|---|
| AIDS/Infection | 124 (52.5) | ||
| Circulatory disease | 43 (18.2) | ||
| Acute myocardial infarction | 8 (3.4) | 3.0 | 1.5-5.8 |
| Respiratory disease | 34 (14.4) | ||
| Neoplasm | 21 (8.9) | ||
| Non-HIV- or liver-related cancers | 14 (5.9) | 2.2 | 1.3-3.7 |
| Hemorrhage | 20 (8.5) | ||
| Intracerebral hemorrhage | 6 (2.5) | ||
| Liver disease | 19 (8.1) | 38 | 24.3-59.7 |
| Central nervous system disease | 17 (7.2) | ||
| Infections other than Pneumocystis or HIV | 13 (5.5) | ||
| Renal disease | 10 (4.2) | 50 | 26.8-92.8 |
| Other causes | 7 (3.0) | ||
| Trauma | 5 (2.1) | ||
| Unknown | 3 (1.3) |
| Cause of death . | Number (%†) of persons (N = 236) . | SMR . | 95% CI . |
|---|---|---|---|
| AIDS/Infection | 124 (52.5) | ||
| Circulatory disease | 43 (18.2) | ||
| Acute myocardial infarction | 8 (3.4) | 3.0 | 1.5-5.8 |
| Respiratory disease | 34 (14.4) | ||
| Neoplasm | 21 (8.9) | ||
| Non-HIV- or liver-related cancers | 14 (5.9) | 2.2 | 1.3-3.7 |
| Hemorrhage | 20 (8.5) | ||
| Intracerebral hemorrhage | 6 (2.5) | ||
| Liver disease | 19 (8.1) | 38 | 24.3-59.7 |
| Central nervous system disease | 17 (7.2) | ||
| Infections other than Pneumocystis or HIV | 13 (5.5) | ||
| Renal disease | 10 (4.2) | 50 | 26.8-92.8 |
| Other causes | 7 (3.0) | ||
| Trauma | 5 (2.1) | ||
| Unknown | 3 (1.3) |
The SMR is the ratio of the observed-to-expected number of deaths from this cause. An SMR >1.0 indicates that there were a greater number of deaths in the cohort than would be expected to occur in a cohort of similarly aged men without hemophilia. CI indicates confidence interval.
Persons may have had more than one cause of death listed.