Adhesion of parasite clone A4 to human umbilical vein endothelial cells in the presence of sulfated glycoconjugates
| Sulfated glycoconjugate . | Exp 1 . | Exp 2 . | Exp 3 . | Exp 4 . | Exp 5 . | Exp 6 . |
|---|---|---|---|---|---|---|
| None | 246 ± 30 | 110 ± 21 | 329 ± 19 | 329 ± 65 | 73 ± 17 | 90 ± 10 |
| Heparin | 767 ± 89 | 71 ± 16 | nd | nd | 474 ± 36 | 143 ± 25 |
| Fucoidan | 965 ± 155 | 187 ± 22 | 515 ± 71 | 331 ± 85 | 442 ± 116 | 136 ± 9 |
| Chondroitin sulfate A | 370 ± 78 | 95 ± 16 | nd | nd | 63 ± 18 | 90 ± 5 |
| Sulfated glycoconjugate . | Exp 1 . | Exp 2 . | Exp 3 . | Exp 4 . | Exp 5 . | Exp 6 . |
|---|---|---|---|---|---|---|
| None | 246 ± 30 | 110 ± 21 | 329 ± 19 | 329 ± 65 | 73 ± 17 | 90 ± 10 |
| Heparin | 767 ± 89 | 71 ± 16 | nd | nd | 474 ± 36 | 143 ± 25 |
| Fucoidan | 965 ± 155 | 187 ± 22 | 515 ± 71 | 331 ± 85 | 442 ± 116 | 136 ± 9 |
| Chondroitin sulfate A | 370 ± 78 | 95 ± 16 | nd | nd | 63 ± 18 | 90 ± 5 |
Adhesion of Plasmodium falciparum-infected erythrocytes (IEs) to resting human umbilical vein endothelial cells was determined in the presence or absence of 100 μg/mL of various sulfated glycoconjugates. Values are the mean (±SD) IEs bound (mm−2) in triplicate determinations. Exp indicates experiment; and nd, not done.