Table 2. Adverse impact of chromosome 13... | American Society of Hematology

Table 2.

Adverse impact of chromosome 13 deletion by risk group

Risk group	Δ13	N	%CR	P	Percent at 5 years ± standard error
Risk group	Δ13	N	%CR	P	CCR	P^*	EFS	P^*	OS	P^*
0^†	No	182	62	.006	52 ± 6.3	.05	41 ± 4.6	.001	62 ± 4.6	.0005
	Yes	29	34		0		0		22 ± 12.7
1^†	No	288	52	.6	37 ± 4.8	.4	34 ± 3.3	.01	52 ± 3.5	.006
	Yes	56	48		0		0		35 ± 8.2
2^†	No	237	42	.03	28 ± 5.7	.09	20 ± 3.3	<.0001	34 ± 4.1	<.0001
	Yes	48	25		0		0		13 ± 5.6
3^†	No	101	28	.2	0	.5	12 ± 4.3	.0002	20 ± 5.1	<.0001
	Yes	20	15		0		0		5 ± 4.9
Total	No	830	47	.0005	35 ± 3.2	.01	28 ± 1.9	<.0001	44 ± 2.2	<.0001
	Yes	163	33		0		0		16 ± 4.9

Risk group	Δ13	N	%CR	P	Percent at 5 years ± standard error
Risk group	Δ13	N	%CR	P	CCR	P^*	EFS	P^*	OS	P^*
0^†	No	182	62	.006	52 ± 6.3	.05	41 ± 4.6	.001	62 ± 4.6	.0005
	Yes	29	34		0		0		22 ± 12.7
1^†	No	288	52	.6	37 ± 4.8	.4	34 ± 3.3	.01	52 ± 3.5	.006
	Yes	56	48		0		0		35 ± 8.2
2^†	No	237	42	.03	28 ± 5.7	.09	20 ± 3.3	<.0001	34 ± 4.1	<.0001
	Yes	48	25		0		0		13 ± 5.6
3^†	No	101	28	.2	0	.5	12 ± 4.3	.0002	20 ± 5.1	<.0001
	Yes	20	15		0		0		5 ± 4.9
Total	No	830	47	.0005	35 ± 3.2	.01	28 ± 1.9	<.0001	44 ± 2.2	<.0001
	Yes	163	33		0		0		16 ± 4.9

Abbreviations: Δ13, chromosome 13 abnormalities; CR, complete remission; CCR, continuous complete remission; EFS, event-free survival; OS, overall survival.

Log-rank test.

†

Number of adverse variables (B2M >2.5 mg/L, CRP >4 mg/L, SDT >12 months).

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