Table 1.

Maximum tolerated dose of rIT in SCID mice

Days after injection PBSKi-4(scFv)–ETA′ (μg)
20 30 40 5060
2  2/2  3/3  3/3  3/3  1/3  0/3  
4 2/2  3/3  3/3  3/3  0/3  0/3  
7  2/2  3/3 3/3  3/3  0/3  0/3  
14  2/2  3/3  3/3  3/3 0/3  0/3 
Days after injection PBSKi-4(scFv)–ETA′ (μg)
20 30 40 5060
2  2/2  3/3  3/3  3/3  1/3  0/3  
4 2/2  3/3  3/3  3/3  0/3  0/3  
7  2/2  3/3 3/3  3/3  0/3  0/3  
14  2/2  3/3  3/3  3/3 0/3  0/3 

Numbers correspond to surviving animals/total.

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