Table 2. Effects on Mpl ligand on... | American Society of Hematology

Table 2.

Effects on Mpl ligand on platelet function

	Baseline	Day 8	Day 12	Day 18
Aggregation^*
ADP (μmol/L)	2.7 ± 1.5	2.1 ± 1.4	2.6 ± 1.9	2.5 ± 2.0
TRAP (μmol/mL)	2.2 ± 1.9	1.5 ± 1.2	1.6 ± 1.4	1.9 ± 1.8
Activation epitopes^†
LIBS	11 ± 7	12 ± 8	18 ± 15	16 ± 11

	Baseline	Day 8	Day 12	Day 18
Aggregation^*
ADP (μmol/L)	2.7 ± 1.5	2.1 ± 1.4	2.6 ± 1.9	2.5 ± 2.0
TRAP (μmol/mL)	2.2 ± 1.9	1.5 ± 1.2	1.6 ± 1.4	1.9 ± 1.8
Activation epitopes^†
LIBS	11 ± 7	12 ± 8	18 ± 15	16 ± 11

Agonist concentration producing half-maximal aggregation.

Binding sites × 10³/platelet.