Clinical characteristics of p210BCR-ABLpositive patients after BMT
Parameters . | p190BCR-ABL Positive . | p190BCR-ABL Negative . | P4-150 . |
---|---|---|---|
Number of patients, n = 24 | 14 | 10 | |
Mean patient age at BMT, y | 33.4 ± 13 | 32.7 ± 7 | NS |
Sex patients, male/female | 6/8 | 3/7 | NS |
Mean time interval between diagnosis and BMT, mo | 24.7 ± 20.8 | 18.3 ± 11.4 | NS |
Clinical phase at BMT, chronic phase/others | 11/3 | 7/3 | NS |
Platelets at BMT, × 109/L | 335.2 ± 239.2 | 437.1 ± 422.8 | NS |
WBC at BMT, × 109/L | 10.1 ± 6.6 | 19.2 ± 22.2 | NS |
Preparative regimen, TBI + CY/BU + CY | 10/4 | 7/3 | NS |
GVHD prophylaxis, short MTX + CsA/CsA alone | 10/4 | 5/5 | NS |
T-cell depletion | 6 | 0 | .0238 |
Acute GVHD | 1 | 2 | NS |
Chronic GVHD | 1 | 7 | .0023 (.0349)4-151 |
Parameters . | p190BCR-ABL Positive . | p190BCR-ABL Negative . | P4-150 . |
---|---|---|---|
Number of patients, n = 24 | 14 | 10 | |
Mean patient age at BMT, y | 33.4 ± 13 | 32.7 ± 7 | NS |
Sex patients, male/female | 6/8 | 3/7 | NS |
Mean time interval between diagnosis and BMT, mo | 24.7 ± 20.8 | 18.3 ± 11.4 | NS |
Clinical phase at BMT, chronic phase/others | 11/3 | 7/3 | NS |
Platelets at BMT, × 109/L | 335.2 ± 239.2 | 437.1 ± 422.8 | NS |
WBC at BMT, × 109/L | 10.1 ± 6.6 | 19.2 ± 22.2 | NS |
Preparative regimen, TBI + CY/BU + CY | 10/4 | 7/3 | NS |
GVHD prophylaxis, short MTX + CsA/CsA alone | 10/4 | 5/5 | NS |
T-cell depletion | 6 | 0 | .0238 |
Acute GVHD | 1 | 2 | NS |
Chronic GVHD | 1 | 7 | .0023 (.0349)4-151 |