Table 4.

Clinical characteristics of p210BCR-ABLpositive patients after BMT

Parameters p190BCR-ABL Positivep190BCR-ABL Negative P4-150
Number of patients, n = 24  14  10  
Mean patient age at BMT, y 33.4 ± 13    32.7 ± 7     NS  
Sex patients, male/female  6/8  3/7  NS  
Mean time interval between diagnosis and BMT, mo  24.7 ± 20.8  18.3 ± 11.4  NS 
Clinical phase at BMT, chronic phase/others  11/3   7/3 NS  
Platelets at BMT, × 109/L 335.2 ± 239.2  437.1 ± 422.8  NS  
WBC at BMT, × 109/L  10.1 ± 6.6   19.2 ± 22.2  NS 
Preparative regimen, TBI + CY/BU + CY  10/4   7/3  NS 
GVHD prophylaxis, short MTX + CsA/CsA alone  10/4   5/5 NS  
T-cell depletion   6   0  .0238  
Acute GVHD  1   2  NS  
Chronic GVHD   1   7 .0023 (.0349)4-151 
Parameters p190BCR-ABL Positivep190BCR-ABL Negative P4-150
Number of patients, n = 24  14  10  
Mean patient age at BMT, y 33.4 ± 13    32.7 ± 7     NS  
Sex patients, male/female  6/8  3/7  NS  
Mean time interval between diagnosis and BMT, mo  24.7 ± 20.8  18.3 ± 11.4  NS 
Clinical phase at BMT, chronic phase/others  11/3   7/3 NS  
Platelets at BMT, × 109/L 335.2 ± 239.2  437.1 ± 422.8  NS  
WBC at BMT, × 109/L  10.1 ± 6.6   19.2 ± 22.2  NS 
Preparative regimen, TBI + CY/BU + CY  10/4   7/3  NS 
GVHD prophylaxis, short MTX + CsA/CsA alone  10/4   5/5 NS  
T-cell depletion   6   0  .0238  
Acute GVHD  1   2  NS  
Chronic GVHD   1   7 .0023 (.0349)4-151 
F4-150

Indicates comparisons between continuous variables by Wilcoxon signed rank test and comparisons between frequencies by Fisher exact test. NS indicates not significant.

F4-151

Indicates that significance is derived from multivariate proportional hazards general linear model analysis.

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