Table 5.

Parameters associated with a longer time to progression and a longer survival in the 124 patients with non-MALT MZL

Time to Progression Survival
Age (y) (<60 vs ≥60)  NS  NS  
Performance status (0-1 vs ≥2)  NS  NS 
Peripheral lymph nodes (yes/no)  P = .001  NS 
Abdominal or thoracic lymph nodes (yes/no)  NS  NS  
Spleen involvement (yes/no)  P = .05   NS  
Stage (I-II vs III-IV)  NS  NS  
Number of extranodal sites (0-1 vs ≥2) NS  NS  
Bulky tumor (yes/no)  NS  NS 
β2-microglobulin level (<3 vs ≥3 mg/L)  NS  NS  
LDH level (normal/abnormal)  NS  NS  
Hemoglobin level (<12 vs ≥12 g/dL)  NS  NS  
Blood involvement (yes/no) P < .05   NS  
International Prognostic Index (0-1 vs 2 vs 3 vs 4-5)  NS  NS 
Time to Progression Survival
Age (y) (<60 vs ≥60)  NS  NS  
Performance status (0-1 vs ≥2)  NS  NS 
Peripheral lymph nodes (yes/no)  P = .001  NS 
Abdominal or thoracic lymph nodes (yes/no)  NS  NS  
Spleen involvement (yes/no)  P = .05   NS  
Stage (I-II vs III-IV)  NS  NS  
Number of extranodal sites (0-1 vs ≥2) NS  NS  
Bulky tumor (yes/no)  NS  NS 
β2-microglobulin level (<3 vs ≥3 mg/L)  NS  NS  
LDH level (normal/abnormal)  NS  NS  
Hemoglobin level (<12 vs ≥12 g/dL)  NS  NS  
Blood involvement (yes/no) P < .05   NS  
International Prognostic Index (0-1 vs 2 vs 3 vs 4-5)  NS  NS 

LDH = lactic dehydrogenase; MALT = mucosa-associated lymphoid tissue; MZL = marginal zone B-cell lymphoma; NS = not significant.

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