Table 1.

Relative suppression of alloreactive T cells by anergic T cells

Exp Stimulator PBMCs no., ×104Anergic cells derived from MLCs blocked for ligands
CD40 + CD86, %CD80 + CD86, % CD40 + CD80 + CD86, %
I  30  41  40  
 2.5  58  30  59  
II  44  22  65  
 2.5  44  16  45  
III  10 21  14  29  
 5  36  20  29 
Exp Stimulator PBMCs no., ×104Anergic cells derived from MLCs blocked for ligands
CD40 + CD86, %CD80 + CD86, % CD40 + CD80 + CD86, %
I  30  41  40  
 2.5  58  30  59  
II  44  22  65  
 2.5  44  16  45  
III  10 21  14  29  
 5  36  20  29 

Relative suppression of cocultures with anergic T cells was compared with the proliferative response of cocultures with control cells, as shown in Figure 5A. (The experiment numbers refer to those given in Figure 5A.)

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