Summary of mutations recurrently affecting the same nucleotide in the 5′ regulatory region of the BCL-6 gene
Position . | Mutation . | Number of Reported Mutations . | Reference . |
---|---|---|---|
84 | G → A | 2 | 15, 26 |
G → C | 1 | 26 | |
G → T | 1 | 27 | |
122 | G → C | 1 | 29 |
G → A* | 3 | 26, 27 | |
123 | C → T | 4 | Present study, 15, 26 |
C → G | 2 | 15, 26 | |
186 | T → C | 3 | Present study, 26 |
190 | T → C | 1 | Present study |
T → A | 2 | 15, 29 | |
365 | G → A | 2 | 29 |
ΔA | 1 | 15 | |
423 | C → G | 2 | 15, 27 |
ΔC | 1 | 29 | |
437 | G → T* | 2 | Present study, 15 |
G → A | 2 | 15, 26 | |
520 | ΔT | 4 | Present study |
748 | ΔT | 2 | 15, 28 |
+T | 2 | 15, 28 | |
T → G | 1 | 27 |
Position . | Mutation . | Number of Reported Mutations . | Reference . |
---|---|---|---|
84 | G → A | 2 | 15, 26 |
G → C | 1 | 26 | |
G → T | 1 | 27 | |
122 | G → C | 1 | 29 |
G → A* | 3 | 26, 27 | |
123 | C → T | 4 | Present study, 15, 26 |
C → G | 2 | 15, 26 | |
186 | T → C | 3 | Present study, 26 |
190 | T → C | 1 | Present study |
T → A | 2 | 15, 29 | |
365 | G → A | 2 | 29 |
ΔA | 1 | 15 | |
423 | C → G | 2 | 15, 27 |
ΔC | 1 | 29 | |
437 | G → T* | 2 | Present study, 15 |
G → A | 2 | 15, 26 | |
520 | ΔT | 4 | Present study |
748 | ΔT | 2 | 15, 28 |
+T | 2 | 15, 28 | |
T → G | 1 | 27 |
Only nucleotide positions affected by mutations 3 or more times are included in the table.
Denotes mutations that were also reported in normal germinal center lymphocytes (14).