Table 1. Weight, sex, E coli dose, and... | American Society of Hematology

Table 1.

Weight, sex, E coli dose, and survival in control and rhATIII groups

	Weight (kg)	Sex	E coli Dose (×10¹⁰ CFU/kg)	E coli Count (2 h) (×10⁷ CFU/kg)	Survival (h)
Control Group No.
7	5.5	F	9.48	15	19.5
11	5	F	10.02	3.65	27
3	6.6	M	7.68	1.72	17
4	6.1	M	8.16	1.28	15
7b	6.8	M	8.15	2.22	18.5
Mean ± SEM	6.0 ± 0.3		8.7 ± 0.45	4.77 ± 2.59	19.4 ± 2
rhATIII Group No.
1	10.2	F	5.45	0.07	>168
2	11.4	F	7.7	0.02	28
3	9.6	M	6.7	0.90	>168
4	10.5	M	5.34	1.39	57
5	6.9	F	5.64	1.15	>168
Mean ± SEM	9.7 ± 0.8^*		6.2 ± 0.5^*	0.70 ± 0.28^*	>117.8 ± 31.1^†

	Weight (kg)	Sex	E coli Dose (×10¹⁰ CFU/kg)	E coli Count (2 h) (×10⁷ CFU/kg)	Survival (h)
Control Group No.
7	5.5	F	9.48	15	19.5
11	5	F	10.02	3.65	27
3	6.6	M	7.68	1.72	17
4	6.1	M	8.16	1.28	15
7b	6.8	M	8.15	2.22	18.5
Mean ± SEM	6.0 ± 0.3		8.7 ± 0.45	4.77 ± 2.59	19.4 ± 2
rhATIII Group No.
1	10.2	F	5.45	0.07	>168
2	11.4	F	7.7	0.02	28
3	9.6	M	6.7	0.90	>168
4	10.5	M	5.34	1.39	57
5	6.9	F	5.64	1.15	>168
Mean ± SEM	9.7 ± 0.8^*		6.2 ± 0.5^*	0.70 ± 0.28^*	>117.8 ± 31.1^†

P < .05 compared with control group (Mann-Whitney U test). Although statistically different, the amounts infused were all within the LD₁₀₀ range (4-8 × 1010 CFU/kg) established over a 10-year period.

†

Indicates P = .002 (log rank test).

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