The relation between current smoking and brain infarction according to the factor XIII Val34Leu polymorphism
| Factor XIII . | Controls . | Cases . | OR (95% CI)3-150,3-151 . | Trend3-150,3-151 . | Subjects Free of Cardio- or Cerebrovascular History . | |||
|---|---|---|---|---|---|---|---|---|
| Controls . | Cases . | OR (95% CI)3-150 . | Trend3-150 . | |||||
| VAL/LEU + LEU/LEU | ||||||||
| Never and ex-smokers | 177 (77.6) | 126 (75.5) | 1.00 (Ref. Group) | 99 (74.4) | 69 (76.7) | 1.00 (Ref. Group) | ||
| Current smokers | ||||||||
| 0-20 PY | 20 (8.9) | 12 (7.2) | 0.98 (0.30-3.17) | 16 (12.0) | 7 (7.8) | 0.31 (0.06-1.73) | ||
| 21-40 PY | 15 (6.6) | 15 (9.0) | 1.29 (0.33-5.14) | 9 (6.8) | 8 (8.9) | 1.98 (0.32-12.34) | ||
| >40 PY | 16 (7.0) | 14 (8.4) | 1.53 (0.53-4.42) | 0.43 | 9 (6.8) | 6 (6.7) | 0.80 (0.17-3.63) | 0.71 |
| VAL/VAL | ||||||||
| Never and ex-smokers | 185 (81.9) | 199 (70.3) | 1.00 (Ref. Group) | 101 (78.9) | 110 (64.7) | 1.00 (Ref. Group) | ||
| Current smokers | ||||||||
| 0-20 PY | 13 (5.8) | 17 (6.0) | 1.17 (0.37-3.70) | 9 (7.0) | 12 (7.1) | 1.60 (0.40-6.46) | ||
| 21-40 PY | 18 (8.0) | 32 (11.3) | 2.69 (1.00-7.27) | 13 (10.2) | 24 (14.1) | 5.91 (1.56-22.36) | ||
| >40 PY | 10 (4.4) | 35 (12.4) | 4.77 (1.57-14.49) | 0.003 | 5 (3.9) | 24 (14.1) | 6.64 (1.75-25.18) | 0.002 |
| Factor XIII . | Controls . | Cases . | OR (95% CI)3-150,3-151 . | Trend3-150,3-151 . | Subjects Free of Cardio- or Cerebrovascular History . | |||
|---|---|---|---|---|---|---|---|---|
| Controls . | Cases . | OR (95% CI)3-150 . | Trend3-150 . | |||||
| VAL/LEU + LEU/LEU | ||||||||
| Never and ex-smokers | 177 (77.6) | 126 (75.5) | 1.00 (Ref. Group) | 99 (74.4) | 69 (76.7) | 1.00 (Ref. Group) | ||
| Current smokers | ||||||||
| 0-20 PY | 20 (8.9) | 12 (7.2) | 0.98 (0.30-3.17) | 16 (12.0) | 7 (7.8) | 0.31 (0.06-1.73) | ||
| 21-40 PY | 15 (6.6) | 15 (9.0) | 1.29 (0.33-5.14) | 9 (6.8) | 8 (8.9) | 1.98 (0.32-12.34) | ||
| >40 PY | 16 (7.0) | 14 (8.4) | 1.53 (0.53-4.42) | 0.43 | 9 (6.8) | 6 (6.7) | 0.80 (0.17-3.63) | 0.71 |
| VAL/VAL | ||||||||
| Never and ex-smokers | 185 (81.9) | 199 (70.3) | 1.00 (Ref. Group) | 101 (78.9) | 110 (64.7) | 1.00 (Ref. Group) | ||
| Current smokers | ||||||||
| 0-20 PY | 13 (5.8) | 17 (6.0) | 1.17 (0.37-3.70) | 9 (7.0) | 12 (7.1) | 1.60 (0.40-6.46) | ||
| 21-40 PY | 18 (8.0) | 32 (11.3) | 2.69 (1.00-7.27) | 13 (10.2) | 24 (14.1) | 5.91 (1.56-22.36) | ||
| >40 PY | 10 (4.4) | 35 (12.4) | 4.77 (1.57-14.49) | 0.003 | 5 (3.9) | 24 (14.1) | 6.64 (1.75-25.18) | 0.002 |