Table 2.

Comparison of amorph Rhnull, regulator Rhnull, and Rhmod RBCs

Phenotype Rh Proteins/Antigens RhAG LW IAPGPB Protein/Antigens Obligate HeterozygotesAltered Gene
Rhnull-amorph  Absent Reduced (20%)  Absent  Reduced by 90%  Reduced by 50% Express one Rh haplotype* RHCE (RHDdeleted)  
     S/s Normal  
     U Weak  
Rhnull-regulator  Absent Absent  Absent  Reduced  Reduced by 70%183 Express both Rh haplotypes  RHAG 
     S/s weak  
     U Absent 
Rhmod Reduced (variable)  Absent or reduced (variable)  Absent or reduced  Reduced (variable)  Reduced (variable)  Express both Rh haplotypes  RHAG 
     S/s Normal  
     U Normal/Weak 
Phenotype Rh Proteins/Antigens RhAG LW IAPGPB Protein/Antigens Obligate HeterozygotesAltered Gene
Rhnull-amorph  Absent Reduced (20%)  Absent  Reduced by 90%  Reduced by 50% Express one Rh haplotype* RHCE (RHDdeleted)  
     S/s Normal  
     U Weak  
Rhnull-regulator  Absent Absent  Absent  Reduced  Reduced by 70%183 Express both Rh haplotypes  RHAG 
     S/s weak  
     U Absent 
Rhmod Reduced (variable)  Absent or reduced (variable)  Absent or reduced  Reduced (variable)  Reduced (variable)  Express both Rh haplotypes  RHAG 
     S/s Normal  
     U Normal/Weak 
*

That is, appear as homozygotes.

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