Comparison of the Frequencies of Different Types of CFC Per 105 Light-Density Human Fetal Liver, Cord Blood, and Adult Marrow Cells and Their Representation in the Total CFC Compartment
Type of CFC Assayed . | No. of CFC Per 105 Cells Assayed . | % of Total CFC . | ||||
---|---|---|---|---|---|---|
Fetal Liver . | Cord Blood . | Adult Marrow . | Fetal Liver . | Cord Blood . | Adult Marrow . | |
CFU-GEMM | 490 ± 320 | 8 ± 4 | 2 ± 1 | 8 ± 5 | 3 ± 1 | 4 ± 5 |
CFU-GM | 2,500 ± 1,400 | 120 ± 30 | 35 ± 6 | 35 ± 6 | 63 ± 3 | 53 ± 4 |
BFU-E | 2,900 ± 800 | 58 ± 10 | 27 ± 5 | 55 ± 5 | 32 ± 3 | 39 ± 5 |
CFU-E | 130 ± 50 | 4 ± 1 | 4 ± 1 | 2 ± 1 | 2 ± 1 | 4 ± 2 |
CFU-Mk (>50 Mk/col) | 21 ± 20 | 15 ± 8 | 14 ± 7 | 0.1 ± 0.1 | 5 ± 2 | 4 ± 2 |
CFU-Mk (3-50 Mk/col) | 120 ± 90 | 26 ± 11 | 35 ± 11 | 0.6 ± 0.5 | 11 ± 5 | 13 ± 3 |
Total | 6,045 ± 2,100 | 190 ± 40 | 66 ± 25 |
Type of CFC Assayed . | No. of CFC Per 105 Cells Assayed . | % of Total CFC . | ||||
---|---|---|---|---|---|---|
Fetal Liver . | Cord Blood . | Adult Marrow . | Fetal Liver . | Cord Blood . | Adult Marrow . | |
CFU-GEMM | 490 ± 320 | 8 ± 4 | 2 ± 1 | 8 ± 5 | 3 ± 1 | 4 ± 5 |
CFU-GM | 2,500 ± 1,400 | 120 ± 30 | 35 ± 6 | 35 ± 6 | 63 ± 3 | 53 ± 4 |
BFU-E | 2,900 ± 800 | 58 ± 10 | 27 ± 5 | 55 ± 5 | 32 ± 3 | 39 ± 5 |
CFU-E | 130 ± 50 | 4 ± 1 | 4 ± 1 | 2 ± 1 | 2 ± 1 | 4 ± 2 |
CFU-Mk (>50 Mk/col) | 21 ± 20 | 15 ± 8 | 14 ± 7 | 0.1 ± 0.1 | 5 ± 2 | 4 ± 2 |
CFU-Mk (3-50 Mk/col) | 120 ± 90 | 26 ± 11 | 35 ± 11 | 0.6 ± 0.5 | 11 ± 5 | 13 ± 3 |
Total | 6,045 ± 2,100 | 190 ± 40 | 66 ± 25 |
Values for the first 4 types of CFC are from 9 fetal liver, 12 cord blood, and 7 adult marrow samples assessed individually. Values for the CFU-Mk are from 13 fetal liver, 6 cord blood, and 8 adult marrow samples. Total refers to CFU-GEMM plus CFU-GM + BFU-E + CFU-E only.