Limit Dilution LTC-IC Evaluation of Transduction Efficacy and Toxicity of MFGS-mCD24 and MFGS-htNGFR Vectors
| LTC-IC Frequency and MFGS-mCD24 Transduction of LTC-IC . | |||
|---|---|---|---|
| Animal No. . | LTC-IC Frequency: Nontransduced PBSC . | LTC-IC Frequency: Transduced PBSC . | % of mCD24+ LTC-IC Among Transduced PBSC . |
| 4630 | 1 in 2,380 | 1 in 5,479 | 60 |
| 4694 | 1 in 558 | 1 in 421 | 40 |
| LTC-IC Frequency and MFGS-htNGFR Transduction of LTC-IC | |||
| Animal No. | LTC-IC Frequency: Nontransduced PBSC | LTC-IC Frequency: Transduced PBSC | % of htNGFR+ LTC-IC Among Transduced PBSC |
| 4630 | 1 in 2,380 | 1 in 20,000 | 0 |
| 4694 | 1 in 558 | 1 in 729 | 0 |
| LTC-IC Frequency and MFGS-mCD24 Transduction of LTC-IC . | |||
|---|---|---|---|
| Animal No. . | LTC-IC Frequency: Nontransduced PBSC . | LTC-IC Frequency: Transduced PBSC . | % of mCD24+ LTC-IC Among Transduced PBSC . |
| 4630 | 1 in 2,380 | 1 in 5,479 | 60 |
| 4694 | 1 in 558 | 1 in 421 | 40 |
| LTC-IC Frequency and MFGS-htNGFR Transduction of LTC-IC | |||
| Animal No. | LTC-IC Frequency: Nontransduced PBSC | LTC-IC Frequency: Transduced PBSC | % of htNGFR+ LTC-IC Among Transduced PBSC |
| 4630 | 1 in 2,380 | 1 in 20,000 | 0 |
| 4694 | 1 in 558 | 1 in 729 | 0 |