Increased Extramedullary CFU-C Frequencies in C57BL/6-lpr/lpr Mice
. | CFU-C/106 Cells . | |||
---|---|---|---|---|
Spleen . | Liver . | WBC . | Peritoneal Cells . | |
C57BL/6-lpr/lpr | 428.9 ± 98.3 | 583.2 ± 150.3 | 83.3 ± 7.2 | 92.2 ± 11.9 |
P < .001 | ||||
C57BL/6 | 36.9 ± 16.8 | 29.5 ± 9.3 | 14.7 ± 1.4 | 13.5 ± 3.3 |
. | CFU-C/106 Cells . | |||
---|---|---|---|---|
Spleen . | Liver . | WBC . | Peritoneal Cells . | |
C57BL/6-lpr/lpr | 428.9 ± 98.3 | 583.2 ± 150.3 | 83.3 ± 7.2 | 92.2 ± 11.9 |
P < .001 | ||||
C57BL/6 | 36.9 ± 16.8 | 29.5 ± 9.3 | 14.7 ± 1.4 | 13.5 ± 3.3 |
Cell populations were prepared from 6-month-old mice as described in Materials and Methods and assayed for CFU-C in complete MethoCult M3434 medium. Data are means ± SEM from 3 separate experiments.