Table 5.

Increased Extramedullary CFU-C Frequencies in C57BL/6-lpr/lpr Mice

CFU-C/106 Cells
Spleen Liver WBC Peritoneal Cells
C57BL/6-lpr/lpr 428.9 ± 98.3  583.2 ± 150.3 83.3 ± 7.2  92.2 ± 11.9 
  P < .001  
C57BL/6 36.9 ± 16.8  29.5 ± 9.3  14.7 ± 1.4 13.5 ± 3.3 
CFU-C/106 Cells
Spleen Liver WBC Peritoneal Cells
C57BL/6-lpr/lpr 428.9 ± 98.3  583.2 ± 150.3 83.3 ± 7.2  92.2 ± 11.9 
  P < .001  
C57BL/6 36.9 ± 16.8  29.5 ± 9.3  14.7 ± 1.4 13.5 ± 3.3 

Cell populations were prepared from 6-month-old mice as described in Materials and Methods and assayed for CFU-C in complete MethoCult M3434 medium. Data are means ± SEM from 3 separate experiments.

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