Table 1.

Superoxide Production in Transgenic PLB-985 Cells

CellsO2 Production (nmol/min/107 cells)
WT gp91 phox PLB-985  55.8 ± 8.8 
Δ488-497 gp91 phox PLB-985  
X-CGD PLB-985  
CellsO2 Production (nmol/min/107 cells)
WT gp91 phox PLB-985  55.8 ± 8.8 
Δ488-497 gp91 phox PLB-985  
X-CGD PLB-985  

The indicated cells were induced for granulocytic differentiation for 5 days with DMF (0.5%), and O2production by intact cells was measured by cytochrome creduction assay. The data represent mean ± SD of 3 separate experiments.

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