Table 1.

Patients’ Outcome After Salvage Therapy

Patient No. Duration of 1st Molecular Remission PML/RARα PCR After Salvage Therapy ABMT Duration of 2nd Molecular RemissionOutcome
Post-ATRA Post-CHT BM Harvest
1  11 Neg  Neg  Neg  Yes  22+  A & W in 2nd molecular remission  
2  11  Pos  Neg  Neg  Yes  17+ A & W in 2nd molecular remission  
3  12  Neg  Neg Neg  Yes  16+  A & W in 2nd molecular remission  
2  Neg  Neg  Neg  Yes  13  Hematologic relapse at 13 mo; 3rd molecular remission with ATRA/MTZ/AraC  
5  11 Neg  Neg  ND  ND  11+  A & W in 2nd molecular remission  
6  3  Neg  Neg  Neg  ND  10+  A & W in 2nd molecular remission  
7  7  Pos  Neg  Neg Yes   9+  A & W in 2nd molecular remission  
8  Pos  Neg  ND  ND   8+  A & W in 2nd molecular remission  
9  3  Neg  Neg  Neg  Yes   7+ A & W in 2nd molecular remission  
10  4  Pos  Neg Neg  Yes   6+  A & W in 2nd molecular remission 
11  3  Neg  Neg  Neg  Yes   6  Hematologic relapse at 8 mo; patient is presently receiving As2O3 therapy  
12  25  Pos Neg  Neg  ND   4+  A & W in 2nd hematologic remission  
13  2  Pos  Pos  ND  ND —  Hematologic relapse at 10 mo; 2nd hematologic remission after As2O3 
14  8  Pos Pos  ND  ND  —  Hemorrhagic death in remission 
Patient No. Duration of 1st Molecular Remission PML/RARα PCR After Salvage Therapy ABMT Duration of 2nd Molecular RemissionOutcome
Post-ATRA Post-CHT BM Harvest
1  11 Neg  Neg  Neg  Yes  22+  A & W in 2nd molecular remission  
2  11  Pos  Neg  Neg  Yes  17+ A & W in 2nd molecular remission  
3  12  Neg  Neg Neg  Yes  16+  A & W in 2nd molecular remission  
2  Neg  Neg  Neg  Yes  13  Hematologic relapse at 13 mo; 3rd molecular remission with ATRA/MTZ/AraC  
5  11 Neg  Neg  ND  ND  11+  A & W in 2nd molecular remission  
6  3  Neg  Neg  Neg  ND  10+  A & W in 2nd molecular remission  
7  7  Pos  Neg  Neg Yes   9+  A & W in 2nd molecular remission  
8  Pos  Neg  ND  ND   8+  A & W in 2nd molecular remission  
9  3  Neg  Neg  Neg  Yes   7+ A & W in 2nd molecular remission  
10  4  Pos  Neg Neg  Yes   6+  A & W in 2nd molecular remission 
11  3  Neg  Neg  Neg  Yes   6  Hematologic relapse at 8 mo; patient is presently receiving As2O3 therapy  
12  25  Pos Neg  Neg  ND   4+  A & W in 2nd hematologic remission  
13  2  Pos  Pos  ND  ND —  Hematologic relapse at 10 mo; 2nd hematologic remission after As2O3 
14  8  Pos Pos  ND  ND  —  Hemorrhagic death in remission 

Abbreviations: ABMT, autologous bone marrow transplantation; ND, not done; A & W, alive and well; CHT, chemotherapy.

or Create an Account

Close Modal
Close Modal