Incidence of p15 and p16 Gene Methylation in BCL and TCL According to the Histopathological Subtypes
| Histology . | n . | p15 Methylated . | p16Methylated . |
|---|---|---|---|
| BCL | 47 | 30/47 (64%) | 15/47 (32%) |
| REAL | |||
| Lymphocytic | 8 | 3/8 (37%) | 0/8 |
| Mantle cell | 6 | 3/6 (50%) | 1/6 (17%) |
| Marginal zone | 1 | 1/1 | 0/1 |
| Follicle center | 14 | 9/14 (64%) | 5/14 (36%) |
| Diffuse large B-cell | 13 | 10/13 (77%) | 6/13 (46%) |
| Immunoblastic | 2 | 2/2 | 2/2 |
| Centroblastic | 9 | 7/9 | 4/9 |
| Mediastinal | 2 | 1/2 | 0/2 |
| T-cell–rich B-cell | 1 | 1/1 | 1/1 |
| High-grade Burkitt-like | 2 | 2/2 | 1/2 |
| Burkitt’s | 2 | 1/2 | 1/2 |
| Kiel | |||
| B-cell, low grade | 29 | 16/29 (55%) | 6/29 (21%) |
| B-cell, high grade | 18 | 14/18 (78%) | 9/18 (50%) |
| TCL | 9 | 4/9 (44%) | 2/9 (22%) |
| PTCL, unspecified | 7 | 2/7 (28%) | 1/7 (14%) |
| ALCL | 2 | 2/2 | 1/2 |
| Total | 56 | 34/56 (61%) | 17/56 (30%) |
| Histology . | n . | p15 Methylated . | p16Methylated . |
|---|---|---|---|
| BCL | 47 | 30/47 (64%) | 15/47 (32%) |
| REAL | |||
| Lymphocytic | 8 | 3/8 (37%) | 0/8 |
| Mantle cell | 6 | 3/6 (50%) | 1/6 (17%) |
| Marginal zone | 1 | 1/1 | 0/1 |
| Follicle center | 14 | 9/14 (64%) | 5/14 (36%) |
| Diffuse large B-cell | 13 | 10/13 (77%) | 6/13 (46%) |
| Immunoblastic | 2 | 2/2 | 2/2 |
| Centroblastic | 9 | 7/9 | 4/9 |
| Mediastinal | 2 | 1/2 | 0/2 |
| T-cell–rich B-cell | 1 | 1/1 | 1/1 |
| High-grade Burkitt-like | 2 | 2/2 | 1/2 |
| Burkitt’s | 2 | 1/2 | 1/2 |
| Kiel | |||
| B-cell, low grade | 29 | 16/29 (55%) | 6/29 (21%) |
| B-cell, high grade | 18 | 14/18 (78%) | 9/18 (50%) |
| TCL | 9 | 4/9 (44%) | 2/9 (22%) |
| PTCL, unspecified | 7 | 2/7 (28%) | 1/7 (14%) |
| ALCL | 2 | 2/2 | 1/2 |
| Total | 56 | 34/56 (61%) | 17/56 (30%) |