Toxicity After the First, Second, and Third MEL100
| . | 1st MEL100 . | 2nd MEL100 . | 3rd MEL100 . |
|---|---|---|---|
| CD34+ reinfused (1 × 106/kg) | 3.8 (1.2-9) | 3.5 (1-8) | 4 (1.1-14) |
| Days with ANC <500/μL | 5 (2-8) | 4 (2-9) | 4 (2-8) |
| Days with Hb <8 g/dL | 1 (0-5) | 0 (0-5) | 0 (0-1) |
| Days with platelets <25,000/μL | 2 (0-8) | 2 (0-7) | 1 (0-7) |
| No. of RBC transfusions | 2 (1-6) | 1 (1-3) | 1 (1-2) |
| No. of platelet transfusions | 1 (1-5) | 1 (1-5) | 1 (1-3) |
| Days with fever >38°C | 4 (2-8) | 3 (1-9) | 2 (1-3) |
| Days with antibiotics use | 7 (4-11) | 6 (5-14) | 7 (5-10) |
| Days of hospitalization | 12 (5-28) | 13 (6-24) | 8 (6-19) |
| Patients transfused with RBC (%) | 54 | 26 | 9 |
| Patients transfused with platelets (%) | 69 | 68 | 55 |
| Patients with fever >38°C (%) | 27 | 18 | 14 |
| Patients hospitalized (%) | 25 | 24 | 23 |
| . | 1st MEL100 . | 2nd MEL100 . | 3rd MEL100 . |
|---|---|---|---|
| CD34+ reinfused (1 × 106/kg) | 3.8 (1.2-9) | 3.5 (1-8) | 4 (1.1-14) |
| Days with ANC <500/μL | 5 (2-8) | 4 (2-9) | 4 (2-8) |
| Days with Hb <8 g/dL | 1 (0-5) | 0 (0-5) | 0 (0-1) |
| Days with platelets <25,000/μL | 2 (0-8) | 2 (0-7) | 1 (0-7) |
| No. of RBC transfusions | 2 (1-6) | 1 (1-3) | 1 (1-2) |
| No. of platelet transfusions | 1 (1-5) | 1 (1-5) | 1 (1-3) |
| Days with fever >38°C | 4 (2-8) | 3 (1-9) | 2 (1-3) |
| Days with antibiotics use | 7 (4-11) | 6 (5-14) | 7 (5-10) |
| Days of hospitalization | 12 (5-28) | 13 (6-24) | 8 (6-19) |
| Patients transfused with RBC (%) | 54 | 26 | 9 |
| Patients transfused with platelets (%) | 69 | 68 | 55 |
| Patients with fever >38°C (%) | 27 | 18 | 14 |
| Patients hospitalized (%) | 25 | 24 | 23 |
Values are the median, with the range in parentheses, unless otherwise specified.
Abbreviations: ANC, absolute neutrophil count; Hb, hemoglobin; RBC, red blood cell.