Table 3.

Spearman Rank Correlation Coefficients of Multidrug Resistance and Efflux Variables

MDR1 Other Multidrug Resistance Proteins CsA-Inhibited Efflux
MM4.17 LRP56 MRP1 DiOC2 Rh123
MDR1 
 MRK16  .84 (<.0001)  .08 (.16)  −.02 (.72) .55 (<.0001)  .58 (<.0001)  
 MM4.17  .10 (.083)  −.05 (.41)  .60 (<.0001) .59 (<.0001)  
Other multidrug resistance proteins 
 LRP56    −.02 (.68)  .01 (.88)  .04 (.49) 
 MRP1     −.05 (.41)  −.03 (.59) 
CsA-inhibited efflux  
 Di(OC)2     .88 (<.0001) 
MDR1 Other Multidrug Resistance Proteins CsA-Inhibited Efflux
MM4.17 LRP56 MRP1 DiOC2 Rh123
MDR1 
 MRK16  .84 (<.0001)  .08 (.16)  −.02 (.72) .55 (<.0001)  .58 (<.0001)  
 MM4.17  .10 (.083)  −.05 (.41)  .60 (<.0001) .59 (<.0001)  
Other multidrug resistance proteins 
 LRP56    −.02 (.68)  .01 (.88)  .04 (.49) 
 MRP1     −.05 (.41)  −.03 (.59) 
CsA-inhibited efflux  
 Di(OC)2     .88 (<.0001) 

Correlation coefficients are based on protein expression or efflux as measured by Kolmogorov-Smirnov D values. Two-tailed P values are shown in parentheses. Numbers of patients range from 295 to 351 depending on availability of data.

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