Table 3. Patient Characteristics... | American Society of Hematology

Table 3.

Patient Characteristics According to Risk Group

	SRG Without Protocol II		SRG With Protocol II (SRT)		RG		EG
	N (44)	%^4-150	N (30)	%^4-150	N (127)	%^4-150	N (17)	%^4-150
Stratification criteria
Risk factor
<0.80	44		30		7		1
0.8-1.19	0		0		69		7
1.2-1.69	0		0		44		8
≥1.70	0		0		7		1
CNS disease	0		0		5		0
Mediastinal mass	0		0		16		3
Blast cells on day 8
<1,000/μL	42		30		121		5
≥1,000/μL	0		0		0		12
Unknown	2		0		0		0
Day 42 BM >5% blasts	0		0		0		2
Other characteristics
Age (yrs)
<1	0	0	0	0	1	1	2	12
1-9	41	93	24	80	101	80	11	65
≥10	3	7	6	20	25	19	4	24
WBC (10⁹/L)
<10	44	100	26	87	25	20	0	0
10-<50	0	0	4	3	68	54	5	30
≥50	0	0	0	0	34	27	12	70
Hb (mmol/L)
<5	27	61	13	43	70	55	8	47
≥5	17	39	17	57	56	45	9	53
Unknown	0		0		1		0
Immunophenotype^4-150
Pro-B-ALL	0	0	1	3	5	4	4	24
c-ALL	29	73	22	76	60	49	4	24
Pre-B-ALL	10	25	6	20	30	25	2	12
T-ALL	0	0	0	0	27	22	7	41
AUL	0	0	0	0	0	0	0	0
Other	1	2	0	0	0	0	0	0
Unknown	4		1		5		0
DNA index^4-150
<1.16	19	76	12	63	73	77	10	77
≥1.16	6	29	7	37	22	23	3	21
Unknown	19		11		32		4
Cellploidy^4-150
Diploid	5	25	4	22	21	23	0	0
Hypodiploid <46	0	0	1	6	4	4	0	0
Hyperdiploid 47-50	4	20	1	6	11	12	1	9
Hyperdiploid >50	10	50	8	44	21	23	5	45.5
Pseudodiploid	1	5	4	22	31	34	5	45.5
Polyploid	0	0	0	0	2	2	0	0
Not evaluable^4-151	16		10		24		5
Not determined	8		2		13		1
Chromosome structural anomalies^4-150
Absent	8	57	7	41	28	34	2	18
Present	6	43	10	59	54	66	9	82
Not evaluable	22		11		32		5
Not determined	8		2		13		1

	SRG Without Protocol II		SRG With Protocol II (SRT)		RG		EG
	N (44)	%^4-150	N (30)	%^4-150	N (127)	%^4-150	N (17)	%^4-150
Stratification criteria
Risk factor
<0.80	44		30		7		1
0.8-1.19	0		0		69		7
1.2-1.69	0		0		44		8
≥1.70	0		0		7		1
CNS disease	0		0		5		0
Mediastinal mass	0		0		16		3
Blast cells on day 8
<1,000/μL	42		30		121		5
≥1,000/μL	0		0		0		12
Unknown	2		0		0		0
Day 42 BM >5% blasts	0		0		0		2
Other characteristics
Age (yrs)
<1	0	0	0	0	1	1	2	12
1-9	41	93	24	80	101	80	11	65
≥10	3	7	6	20	25	19	4	24
WBC (10⁹/L)
<10	44	100	26	87	25	20	0	0
10-<50	0	0	4	3	68	54	5	30
≥50	0	0	0	0	34	27	12	70
Hb (mmol/L)
<5	27	61	13	43	70	55	8	47
≥5	17	39	17	57	56	45	9	53
Unknown	0		0		1		0
Immunophenotype^4-150
Pro-B-ALL	0	0	1	3	5	4	4	24
c-ALL	29	73	22	76	60	49	4	24
Pre-B-ALL	10	25	6	20	30	25	2	12
T-ALL	0	0	0	0	27	22	7	41
AUL	0	0	0	0	0	0	0	0
Other	1	2	0	0	0	0	0	0
Unknown	4		1		5		0
DNA index^4-150
<1.16	19	76	12	63	73	77	10	77
≥1.16	6	29	7	37	22	23	3	21
Unknown	19		11		32		4
Cellploidy^4-150
Diploid	5	25	4	22	21	23	0	0
Hypodiploid <46	0	0	1	6	4	4	0	0
Hyperdiploid 47-50	4	20	1	6	11	12	1	9
Hyperdiploid >50	10	50	8	44	21	23	5	45.5
Pseudodiploid	1	5	4	22	31	34	5	45.5
Polyploid	0	0	0	0	2	2	0	0
Not evaluable^4-151	16		10		24		5
Not determined	8		2		13		1
Chromosome structural anomalies^4-150
Absent	8	57	7	41	28	34	2	18
Present	6	43	10	59	54	66	9	82
Not evaluable	22		11		32		5
Not determined	8		2		13		1

Percentage of patients with available information.

Including Down’s syndrome.