Table 2.

Effects of CyPB on Platelet Aggregation and Degranulation

Platelet Aggregation (%) 5-HT Release (%)
No ligand 6 ± 5  8.4 ± 4.5  
CyPB  
 10 nmol/L  5 ± 4 11.1 ± 3.5  
 50 nmol/L  6 ± 4  10.0 ± 2.5 
 500 nmol/L  7 ± 3  10.1 ± 3.4  
Thrombin: 0.05 U/mL  26 ± 6  12 ± 5  
 +CyPB 50 nmol/L  28 ± 5 16 ± 3.5  
 +CyPB 500 nmol/L  25 ± 8  14 ± 4 
Thrombin: 0.5 U/mL  84 ± 5  89 ± 6 
Platelet Aggregation (%) 5-HT Release (%)
No ligand 6 ± 5  8.4 ± 4.5  
CyPB  
 10 nmol/L  5 ± 4 11.1 ± 3.5  
 50 nmol/L  6 ± 4  10.0 ± 2.5 
 500 nmol/L  7 ± 3  10.1 ± 3.4  
Thrombin: 0.05 U/mL  26 ± 6  12 ± 5  
 +CyPB 50 nmol/L  28 ± 5 16 ± 3.5  
 +CyPB 500 nmol/L  25 ± 8  14 ± 4 
Thrombin: 0.5 U/mL  84 ± 5  89 ± 6 

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