Table 2.
Effects of CyPB on Platelet Aggregation and Degranulation
.
Platelet Aggregation (%)
.
5-HT Release (%)
.
No ligand
6 ± 5
8.4 ± 4.5
CyPB
10 nmol/L
5 ± 4
11.1 ± 3.5
50 nmol/L
6 ± 4
10.0 ± 2.5
500 nmol/L
7 ± 3
10.1 ± 3.4
Thrombin: 0.05 U/mL
26 ± 6
12 ± 5
+CyPB 50 nmol/L
28 ± 5
16 ± 3.5
+CyPB 500 nmol/L
25 ± 8
14 ± 4
Thrombin: 0.5 U/mL
84 ± 5
89 ± 6
.
Platelet Aggregation (%)
.
5-HT Release (%)
.
No ligand
6 ± 5
8.4 ± 4.5
CyPB
10 nmol/L
5 ± 4
11.1 ± 3.5
50 nmol/L
6 ± 4
10.0 ± 2.5
500 nmol/L
7 ± 3
10.1 ± 3.4
Thrombin: 0.05 U/mL
26 ± 6
12 ± 5
+CyPB 50 nmol/L
28 ± 5
16 ± 3.5
+CyPB 500 nmol/L
25 ± 8
14 ± 4
Thrombin: 0.5 U/mL
84 ± 5
89 ± 6
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