MLL Fusion Proteins That May Affect Chromatin Remodeling
| Fusion . | Karyotype . | Potential Target Pathway . |
|---|---|---|
| All MLL-fusions | Any 11q23 abnormality | SWI/SNF |
| MLL-AF9 | t(9;11)(p22;q23) | SWI/SNF |
| MLL-ENL | t(11;19)(q23;p13.3) | SWI/SNF and/or HAT |
| MLL-CBP | t(11;16)(q23;p13) | HAT |
| MLL-p300 | t(11;23)(q23;q13) | HAT |
| Fusion . | Karyotype . | Potential Target Pathway . |
|---|---|---|
| All MLL-fusions | Any 11q23 abnormality | SWI/SNF |
| MLL-AF9 | t(9;11)(p22;q23) | SWI/SNF |
| MLL-ENL | t(11;19)(q23;p13.3) | SWI/SNF and/or HAT |
| MLL-CBP | t(11;16)(q23;p13) | HAT |
| MLL-p300 | t(11;23)(q23;q13) | HAT |