Table 2.

Statistical Comparisons of Table 1 Mean Busulfan CL/F Among Underweight, Normal, Obese, and Severely Obese Patients

BMI Category (1) BMI Category (2) % Difference in Absolute CL/F* (mL/min) P% Difference in CL/F/BW* (mL/min/kg) P
Underweight  Normal −12.4  1.000  24.5  .000  
 Obese  −32.0 .021  33.3  .000  
 Severely obese  −47.9  .004 40.1  .000  
Normal  Underweight  11.1  1.000 −32.4  .000  
 Obese  −17.4  .000  11.7 .000  
 Severely obese  −31.6  .001  20.7  .014 
Obese  Underweight  24.2  .021  −50.0  .000 
 Normal  14.8  .000  −13.3  .000  
 Severely obese  −12.1  .571  10.2  1.000  
Severely  obese Underweight  32.4  .004  −67.0  .000  
 Normal 24.0  .001  −26.1  .014  
 Obese  10.8  .571 −11.3  1.000 
BMI Category (1) BMI Category (2) % Difference in Absolute CL/F* (mL/min) P% Difference in CL/F/BW* (mL/min/kg) P
Underweight  Normal −12.4  1.000  24.5  .000  
 Obese  −32.0 .021  33.3  .000  
 Severely obese  −47.9  .004 40.1  .000  
Normal  Underweight  11.1  1.000 −32.4  .000  
 Obese  −17.4  .000  11.7 .000  
 Severely obese  −31.6  .001  20.7  .014 
Obese  Underweight  24.2  .021  −50.0  .000 
 Normal  14.8  .000  −13.3  .000  
 Severely obese  −12.1  .571  10.2  1.000  
Severely  obese Underweight  32.4  .004  −67.0  .000  
 Normal 24.0  .001  −26.1  .014  
 Obese  10.8  .571 −11.3  1.000 
*

The percent difference in CL/F = ( BMI category (1) − BMI category (2)/BMI category (1)) × 100.