Table 2. Summary of Effects of Protease... | American Society of Hematology

Table 2.

Summary of Effects of Protease Inhibitors in Platelet Activation Events

Agonist-Induced Event	Effect of
Agonist-Induced Event	DEVD-fmk	Calpeptin
α-Granule release	No effect^*	No effect²⁷
Shape change	No effect^*	No effect²⁷
Aggregation	No effect^*	No effect²⁷
PS exposure	Inhibited^*	Enhanced¹⁸^*
Filopodia extension	Not examined	Enhanced³⁶
Moesin cleavage	Inhibited^*	Inhibited^†
Microparticle release	Inhibited^*	Inhibited17 18 ^*

Agonist-Induced Event	Effect of
Agonist-Induced Event	DEVD-fmk	Calpeptin
α-Granule release	No effect^*	No effect²⁷
Shape change	No effect^*	No effect²⁷
Aggregation	No effect^*	No effect²⁷
PS exposure	Inhibited^*	Enhanced¹⁸^*
Filopodia extension	Not examined	Enhanced³⁶
Moesin cleavage	Inhibited^*	Inhibited^†
Microparticle release	Inhibited^*	Inhibited17 18 ^*

Findings of the present study.

Shcherbina et al16a and present study (data not shown).