Table 4.

Usage of Different Jh Gene Segments in Incomplete and Complete Cross-Lineage IGH Gene Rearrangements in T-ALL as Compared With Precursor-B-ALL, Human BM Precursor-B Cells, and PB B Lymphocytes

Jh Segment T-ALL (n = 39)PrecursorB-ALL Human BM Precursor-B Cells Human PB B Lymphocytes
Jh1  13% (5)  2%  0% 1%  
Jh2  15% (6)  2%  4%  0% 
Jh3  10% (4)  11%  14%  9% 
Jh4  33% (13)  32%  32%  53% 
Jh5  8% (3)  22%  17%  15% 
Jh6  21% (8)  32%  33%  22% 
Jh Segment T-ALL (n = 39)PrecursorB-ALL Human BM Precursor-B Cells Human PB B Lymphocytes
Jh1  13% (5)  2%  0% 1%  
Jh2  15% (6)  2%  4%  0% 
Jh3  10% (4)  11%  14%  9% 
Jh4  33% (13)  32%  32%  53% 
Jh5  8% (3)  22%  17%  15% 
Jh6  21% (8)  32%  33%  22% 

The B-lineage data were obtained in comparable PCR-based studies by Steenbergen et al37 for precursor-B-ALL, by Raaphorst et al36 for human BM precursor-B cells, and by Yamada et al35 for human blood B lymphocytes.

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