Loss of Heterozygosity in Nf1+/− Mice
| Genotype and Treatment . | No. of Mice . | No. With LOH/ No. With Leukemia . | No. With LOH/ No. Without Leukemia . |
|---|---|---|---|
| 129/Sv | |||
| None | 46 | 5/8 (62%) | 10/38 (26%) |
| Etoposide | 32 | 7/8 (87%) | 1/24 (4%) |
| CY | 12 | 5/7 (71%) | 4/5 (80%) |
| 129/Sv × C57BL/6 | |||
| None | 12 | 0/0 | 1/12 (8%) |
| CY | 25 | 2/7 (28%) | 1/18 (5%) |
| All mice | 19/30 (63%) | 17/97 (17%) |
| Genotype and Treatment . | No. of Mice . | No. With LOH/ No. With Leukemia . | No. With LOH/ No. Without Leukemia . |
|---|---|---|---|
| 129/Sv | |||
| None | 46 | 5/8 (62%) | 10/38 (26%) |
| Etoposide | 32 | 7/8 (87%) | 1/24 (4%) |
| CY | 12 | 5/7 (71%) | 4/5 (80%) |
| 129/Sv × C57BL/6 | |||
| None | 12 | 0/0 | 1/12 (8%) |
| CY | 25 | 2/7 (28%) | 1/18 (5%) |
| All mice | 19/30 (63%) | 17/97 (17%) |