Table 2. CBDCA and PIXY321 Effects on... | American Society of Hematology

Table 2.

CBDCA and PIXY321 Effects on ANC

Comparison (study portion-cycle)^*	No. of Patients	Mean ANC Nadir (1,000 cells/μL)^†	P Value	Mean Days of ANC <500/μL^†	P Value	Mean Days to ANC >1,500/μL^†	P Value
A-1 v A-2	20 v 20	0.65 (±0.14)v 1.39 (±0.33)	.02	3.3 (±1.0) v1.7 (±0.6)	.03	22 (±2) v 14 (±2)	.004
A-1 v B-1	20 v 11	0.65 (±0.14)v 2.88 (±0.98)	.003	3.3 (±1.0) v0.8 (±0.6)	.11	22 (±2) v 8 (±3)	<.001
B-1 v B-2	11 v 11	2.88 (±0.98) v 0.92 (±0.26)	.008	0.8 (±0.6) v 3.6 (±1.4)	.13	8 (±3)v 22 (±4)	.002
A-2 v B-2	20 v 11	1.39 (±0.33) v 0.92 (±0.26)	.36	1.7 (±0.6) v 3.6 (±1.4)	.17	14 (±2) v 22 (±4)	.07

Comparison (study portion-cycle)^*	No. of Patients	Mean ANC Nadir (1,000 cells/μL)^†	P Value	Mean Days of ANC <500/μL^†	P Value	Mean Days to ANC >1,500/μL^†	P Value
A-1 v A-2	20 v 20	0.65 (±0.14)v 1.39 (±0.33)	.02	3.3 (±1.0) v1.7 (±0.6)	.03	22 (±2) v 14 (±2)	.004
A-1 v B-1	20 v 11	0.65 (±0.14)v 2.88 (±0.98)	.003	3.3 (±1.0) v0.8 (±0.6)	.11	22 (±2) v 8 (±3)	<.001
B-1 v B-2	11 v 11	2.88 (±0.98) v 0.92 (±0.26)	.008	0.8 (±0.6) v 3.6 (±1.4)	.13	8 (±3)v 22 (±4)	.002
A-2 v B-2	20 v 11	1.39 (±0.33) v 0.92 (±0.26)	.36	1.7 (±0.6) v 3.6 (±1.4)	.17	14 (±2) v 22 (±4)	.07

Cycles with PIXY321 are in bold.

Values in parenthesis represent standard errors of the mean.