Table 1.

Effect of MK-801 (100 μmol/L) on PMA-Stimulated Increases in Size and CD41 (GPIIb/IIIa) Expression of MEG-01 Cells

Treatment Mean Forward Scatter*CD41+ Events (%)
None  294.2 ± 2.8 (4)  1.1 ± 0.1 (3)  
+PMA 479.6 ± 36.7 (4)  33.9 ± 0.5 (3)  
+PMA + MK-801 326.0 ± 1.9 (4)† 19.8 ± 0.7 (3)‡ 
Treatment Mean Forward Scatter*CD41+ Events (%)
None  294.2 ± 2.8 (4)  1.1 ± 0.1 (3)  
+PMA 479.6 ± 36.7 (4)  33.9 ± 0.5 (3)  
+PMA + MK-801 326.0 ± 1.9 (4)† 19.8 ± 0.7 (3)‡ 
*

Mean values ± SEM; number of replicates in parentheses.

Statistically significant differences were observed (

†

P < .05 and

‡

P < .005) vPMA-stimulated MEG-01s in the absence of MK-801.

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