Clinical Findings and Outcome of ALK+Lymphoma
| Characteristic . | ALK+ . | ||
|---|---|---|---|
| Alive (N = 40) . | Died (N = 13) . | P . | |
| Sex | |||
| M | 30 | 10 | NS |
| F | 10 | 3 | |
| Age (yr) | |||
| ≤35 | 36 | 11 | NS |
| >35 | 4 | 2 | |
| Performance status | |||
| 0-1 | 22 | 3 | .008 |
| >1 | 11 | 10 | |
| B symptoms | |||
| No | 11 | 2 | NS |
| Yes | 29 | 11 | |
| Bulky disease | |||
| No | 30 | 10 | NS |
| Yes | 10 | 3 | |
| Extranodal sites | |||
| No | 21 | 0 | .001 |
| Yes | 19 | 13 | |
| Extranodal sites | |||
| Skin | 6 | 5 | |
| Bone | 6 | 3 | |
| Bone marrow | 3 | 3 | |
| Lung | 3 | 3 | |
| Ann Arbor stage | |||
| I-II | 14 | 1 | NS |
| III-IV | 26 | 12 | |
| LDH level | |||
| <1× normal | 21 | 6 | NS |
| >1× normal | 15 | 5 | |
| International Prognostic Index | |||
| 0-1 (low/low intermediate) | 24 | 1 | .001 |
| ≥2 (high/high intermediate) | 13 | 12 | |
| Characteristic . | ALK+ . | ||
|---|---|---|---|
| Alive (N = 40) . | Died (N = 13) . | P . | |
| Sex | |||
| M | 30 | 10 | NS |
| F | 10 | 3 | |
| Age (yr) | |||
| ≤35 | 36 | 11 | NS |
| >35 | 4 | 2 | |
| Performance status | |||
| 0-1 | 22 | 3 | .008 |
| >1 | 11 | 10 | |
| B symptoms | |||
| No | 11 | 2 | NS |
| Yes | 29 | 11 | |
| Bulky disease | |||
| No | 30 | 10 | NS |
| Yes | 10 | 3 | |
| Extranodal sites | |||
| No | 21 | 0 | .001 |
| Yes | 19 | 13 | |
| Extranodal sites | |||
| Skin | 6 | 5 | |
| Bone | 6 | 3 | |
| Bone marrow | 3 | 3 | |
| Lung | 3 | 3 | |
| Ann Arbor stage | |||
| I-II | 14 | 1 | NS |
| III-IV | 26 | 12 | |
| LDH level | |||
| <1× normal | 21 | 6 | NS |
| >1× normal | 15 | 5 | |
| International Prognostic Index | |||
| 0-1 (low/low intermediate) | 24 | 1 | .001 |
| ≥2 (high/high intermediate) | 13 | 12 | |
Abbreviation: NS, not significant.