Total Numbers and Frequencies of T-Cell Precursors Recovered From Paraaortic Foci, Blood, Spleen, and BM From Day 4 to Day 23 of Development
| Tissue Analyzed . | Days of Development . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| E4 . | E7 . | E10 . | E11 . | E12 . | E13 . | E14 . | E15 . | E16 . | E19 . | E23 . | |
| Paraaortic foci | 10 | 7 | |||||||||
| Blood | 75 | 25 | 172 | 136 | 640 | 258 | 96 | <55 | 5,712 | 5,530 | |
| (0.3 × 10−6) | (0.06 × 10−6) | (0.31 × 10−6) | (0.2 × 10−6) | (0.86 × 10−6) | (0.32 × 10−6) | (0.11 × 10−6) | (<0.06 × 10−6) | (2.5 × 10−6) | (2.0 × 10−6) | ||
| Spleen | 1 | 55 | 4,500 | 9,200 | 8,000 | 14,600 | |||||
| (3.3 × 10−6) | (46 × 10−6) | (1,400 × 10−6) | (970 × 10−6) | (930 × 10−6) | (2,000 × 10−6) | ||||||
| BM | 20 | 5,500 | 13,900 | 23,600 | 65,400 | ||||||
| (33 × 10−6) | (1,400 × 10−6) | (640 × 10−6) | (1,000 × 10−6) | (2,000 × 10−6) | |||||||
| Tissue Analyzed . | Days of Development . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| E4 . | E7 . | E10 . | E11 . | E12 . | E13 . | E14 . | E15 . | E16 . | E19 . | E23 . | |
| Paraaortic foci | 10 | 7 | |||||||||
| Blood | 75 | 25 | 172 | 136 | 640 | 258 | 96 | <55 | 5,712 | 5,530 | |
| (0.3 × 10−6) | (0.06 × 10−6) | (0.31 × 10−6) | (0.2 × 10−6) | (0.86 × 10−6) | (0.32 × 10−6) | (0.11 × 10−6) | (<0.06 × 10−6) | (2.5 × 10−6) | (2.0 × 10−6) | ||
| Spleen | 1 | 55 | 4,500 | 9,200 | 8,000 | 14,600 | |||||
| (3.3 × 10−6) | (46 × 10−6) | (1,400 × 10−6) | (970 × 10−6) | (930 × 10−6) | (2,000 × 10−6) | ||||||
| BM | 20 | 5,500 | 13,900 | 23,600 | 65,400 | ||||||
| (33 × 10−6) | (1,400 × 10−6) | (640 × 10−6) | (1,000 × 10−6) | (2,000 × 10−6) | |||||||
Estimations were performed using the standard curve presented in Figs 1 and 3 and data presented in Table 1. These estimations were performed for each individual recipient and the mean was then calculated. Data are given in number of T-cell precursors per embryo. ( ) corresponds to the frequency of T-cell precursors in a given tissue. For convenience, E23 corresponds to 2-day-old chicks.