Table 2.

HB-EGF, HER-1, HER-4, and CD9 Expression in Cell Lines in Basal Conditions

Patient No. Cell Lines*HB-EGF mRNADT SensitivityHER-12-153HER-4 mRNACD92-153
1  U937  +  +  −  +  −  
2  THP-1  +  −  −  +  
3  ML-3  +  +  −  ± −  
4  HL-60  +  +  −  ±  −  
K562  +  −  −  −  +  
6  Jurkat  +  −  −  +  
7  Karpas 299  +  +  − +  −  
8  L540  +  +  −  −  −  
L428  −  −  −  −  −  
10  Raji −  −  −  −  −  
11  2C8  −  − −  −  nd 
Patient No. Cell Lines*HB-EGF mRNADT SensitivityHER-12-153HER-4 mRNACD92-153
1  U937  +  +  −  +  −  
2  THP-1  +  −  −  +  
3  ML-3  +  +  −  ± −  
4  HL-60  +  +  −  ±  −  
K562  +  −  −  −  +  
6  Jurkat  +  −  −  +  
7  Karpas 299  +  +  − +  −  
8  L540  +  +  −  −  −  
L428  −  −  −  −  −  
10  Raji −  −  −  −  −  
11  2C8  −  − −  −  nd 

Abbreviation: nd, not done.

*

See Materials and Methods for lineage assignment.

By RT-PCR.

DT sensitivity was evaluated by the MTT assay (see Table 1).

F2-153

By flow cytometry.

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