Table 3. Correlations of FPGS, FPGH, and... | American Society of Hematology

Table 3.

Correlations of FPGS, FPGH, and the Ratio FPGS/FPGH with MTX Accumulation and Polyglutamylation Data in Childhood Leukemia Samples

	c/preB-ALL^3-150		T-ALL^3-151		AML^3-152		c/preB-, T-ALL, and AML
	acc. Glu_1-6r	acc. Glu_4-6r	acc. Glu_1-6r	acc. Glu_4-6r	acc. Glu_1-6r	acc. Glu_4-6r	acc. Glu_1-6r	acc. Glu_4-6r
Normalized to cell number
FPGS	.62^3-154	.49^3-153	.31	−.03	.60	.20	.67^3-154	.49^3-154
FPGH	.12	.28	−.03	−.45	.18	.08	−.04	−.34^3-153
FPGS/FPGH	.55^3-153	.27	.71	.70	.60	.02	.63^3-154	.61^3-154
Normalized to mg protein
FPGS	.58^3-154	.59^3-153	.04	−.37	.60	.33	.57^3-154	.56^3-154
FPGH	.10	.27	−.15	−.53	−.04	.08	−.06	−.21
FPGS/FPGH	.53^3-153	.30	0	.70	.55	.17	.52^3-154	.67^3-154

	c/preB-ALL^3-150		T-ALL^3-151		AML^3-152		c/preB-, T-ALL, and AML
	acc. Glu_1-6r	acc. Glu_4-6r	acc. Glu_1-6r	acc. Glu_4-6r	acc. Glu_1-6r	acc. Glu_4-6r	acc. Glu_1-6r	acc. Glu_4-6r
Normalized to cell number
FPGS	.62^3-154	.49^3-153	.31	−.03	.60	.20	.67^3-154	.49^3-154
FPGH	.12	.28	−.03	−.45	.18	.08	−.04	−.34^3-153
FPGS/FPGH	.55^3-153	.27	.71	.70	.60	.02	.63^3-154	.61^3-154
Normalized to mg protein
FPGS	.58^3-154	.59^3-153	.04	−.37	.60	.33	.57^3-154	.56^3-154
FPGH	.10	.27	−.15	−.53	−.04	.08	−.06	−.21
FPGS/FPGH	.53^3-153	.30	0	.70	.55	.17	.52^3-154	.67^3-154

Number of c/preB-ALL samples were ranging from 16 to 37.

Number of T-ALL samples were ranging from 5 to 12.

Number of AML samples were ranging from 8 to 13.

Significance at the level of 0.05 (two-tailed).

Significance at the level of 0.01 (two-tailed).