Expression of RHAMM on B-Lineage Cells in MM
| Cell Type (no. of patients) . | % Expressing RHAMM . | ||
|---|---|---|---|
| 25th Percentile . | Median . | 75th Percentile . | |
| MM | |||
| BM plasma cells (15)* | 41 | 74† | 93 |
| Blood B cells (90) | 28 | 57† | 92 |
| Normal donors | |||
| B cells (12) | 1 | 3.5 | 9 |
| Cell Type (no. of patients) . | % Expressing RHAMM . | ||
|---|---|---|---|
| 25th Percentile . | Median . | 75th Percentile . | |
| MM | |||
| BM plasma cells (15)* | 41 | 74† | 93 |
| Blood B cells (90) | 28 | 57† | 92 |
| Normal donors | |||
| B cells (12) | 1 | 3.5 | 9 |
PBMC or BMC were stained in two color immunofluorescence as indicated in Materials and Methods. Files were gated for B or plasma cells and the expression of RHAMM plotted as a histogram (as in Fig1), in comparison to identically gated isotype-matched control staining.
From Turley et al.22
P < .001 as compared with normal B cells.