Ploidy, Proliferation and Apoptosis Analysis by Flow Cytometry of sARL (1-10), a Cell Line (SL-C18), and Normal Tissues
| Samples . | DNA Index . | % of S Phase . | % of G2 Phase . | % of Apoptosis . |
|---|---|---|---|---|
| 1 | 1.0 | 17.65 | 4.35 | 1.25 |
| 2 | 1.0 | 9.1 | 1.8 | 2.47 |
| 3 | 1.0 | 9.0 | 2.3 | 2.72 |
| 4 | 1.0 | 16.9 | 3.45 | 5.48 |
| 5 | 1.0 | 18.7 | 3.5 | 6.73 |
| 6 | 1.0 | 14.85 | 3.1 | 1.85 |
| 7 | 1.0 | 14.35 | 2.9 | 5.36 |
| 8 | 1.0 | 6.6 | 1.85 | 12.36 |
| 9 M | 1.0, 1.07, and 2.07 | 31.03-150 | 6.13-150 | 24.2 |
| 9 K | 1.0 and 2.16 | 22.53-150 | 6.93-150 | — |
| 9 E | 1.0, 2.0, 4.0, and 1.09 | 24.53-150 | 9.93-150 | — |
| 10 | 1.0 | 9.95 | 1.8 | 1.5 |
| SL-C183-151 | 1.0 | 30 | 3.2 | — |
| Monkey gut | 1.0 | 3.2 | 1 | 1.41 |
| Monkey heart | 1.0, 2.0, 4.0, and 8.0 | — | — | — |
| Human tonsil | 1.0 | 7.7 | 2.15 | 2.68 |
| Samples . | DNA Index . | % of S Phase . | % of G2 Phase . | % of Apoptosis . |
|---|---|---|---|---|
| 1 | 1.0 | 17.65 | 4.35 | 1.25 |
| 2 | 1.0 | 9.1 | 1.8 | 2.47 |
| 3 | 1.0 | 9.0 | 2.3 | 2.72 |
| 4 | 1.0 | 16.9 | 3.45 | 5.48 |
| 5 | 1.0 | 18.7 | 3.5 | 6.73 |
| 6 | 1.0 | 14.85 | 3.1 | 1.85 |
| 7 | 1.0 | 14.35 | 2.9 | 5.36 |
| 8 | 1.0 | 6.6 | 1.85 | 12.36 |
| 9 M | 1.0, 1.07, and 2.07 | 31.03-150 | 6.13-150 | 24.2 |
| 9 K | 1.0 and 2.16 | 22.53-150 | 6.93-150 | — |
| 9 E | 1.0, 2.0, 4.0, and 1.09 | 24.53-150 | 9.93-150 | — |
| 10 | 1.0 | 9.95 | 1.8 | 1.5 |
| SL-C183-151 | 1.0 | 30 | 3.2 | — |
| Monkey gut | 1.0 | 3.2 | 1 | 1.41 |
| Monkey heart | 1.0, 2.0, 4.0, and 8.0 | — | — | — |
| Human tonsil | 1.0 | 7.7 | 2.15 | 2.68 |
Most of the tumors show a diploid cellular DNA content and intermediate fractions of proliferative cells (range 8.45% to 20.35%). One case (no. 9) showed two aneuploid tumor cell populations and a high average fraction of proliferative cells (mean = 33.6%).
Abbreviations: M, mediatinum; K, kidney; E, endocardium.
Average values that are related to the combined cell populations.
Derived from tumor 10.