Risk of Second Malignancies After HD Treatment
| Site or Type . | Relative Risk . | Absolute Excess Risk9-150 (per 10,000 patients per yr) . |
|---|---|---|
| All malignancies | 3.5 | 56.2 |
| ANLL | 70.8 | 15.5 |
| NHL | 18.6 | 10.7 |
| Solid tumors | 2.4 | 29.3 |
| Lung | 4.2 | 13.5 |
| Breast | 2.5 | 11.3 |
| GI | 2.5 | 5.8 |
| Sarcoma | 7.0 | 1.0 |
| Thyroid | 4.7 | 0.5 |
| Melanoma | 4.2 | 1.6 |
| Site or Type . | Relative Risk . | Absolute Excess Risk9-150 (per 10,000 patients per yr) . |
|---|---|---|
| All malignancies | 3.5 | 56.2 |
| ANLL | 70.8 | 15.5 |
| NHL | 18.6 | 10.7 |
| Solid tumors | 2.4 | 29.3 |
| Lung | 4.2 | 13.5 |
| Breast | 2.5 | 11.3 |
| GI | 2.5 | 5.8 |
| Sarcoma | 7.0 | 1.0 |
| Thyroid | 4.7 | 0.5 |
| Melanoma | 4.2 | 1.6 |
Abbreviation: GI, gastrointestinal tract.
Absolute (excess) risk per 10,000 patient years = [observed events − expected events/person-years] × 10,000. The absolute risk divided by 100 is the percentage likelihood of an event per year of follow-up for an individual patient.
Data derived from reference 155, except for GI tumor data derived from reference 171.