Table 2.

Colony Formation of BM Cells From 5-FU–Treated Mice

Mice Cytokines No. of Colonies/1 × 105 Cells
GM Mk Mix BlastTotal
Littermate  No factor  0  0  0  0  
 hG-CSF  0  0  0  0  0  
 mIL-3 40 ± 6  2 ± 1  4 ± 2  4 ± 2  50 ± 8 
Tg mouse  No factor  0  0  0  0  0  
 hG-CSF 16 ± 4  4 ± 1  4 ± 2  3 ± 1  27 ± 6 
 mIL-3  38 ± 5  2 ± 1  5 ± 2  4 ± 2 49 ± 7 
Mice Cytokines No. of Colonies/1 × 105 Cells
GM Mk Mix BlastTotal
Littermate  No factor  0  0  0  0  
 hG-CSF  0  0  0  0  0  
 mIL-3 40 ± 6  2 ± 1  4 ± 2  4 ± 2  50 ± 8 
Tg mouse  No factor  0  0  0  0  0  
 hG-CSF 16 ± 4  4 ± 1  4 ± 2  3 ± 1  27 ± 6 
 mIL-3  38 ± 5  2 ± 1  5 ± 2  4 ± 2 49 ± 7 

BM cells (1 × 105) were incubated in the presence of hG-CSF (20 ng/mL) or mIL-3 (10 ng/mL). The values are the mean ± SD of the data obtained from three independent experiments.

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