Table 2.

Expression of CD95 and CD95L on Leukemic LGL

Samples Phenotype (%)
CD95CD57 CD57/CD95*CD95L
PBMC  35 ± 11 6 ± 2  32 ± 12  2 ± 1  
PBMC post-PHA/IL-2 94 ± 3   9 ± 2  90 ± 3   42 ± 5  
CD3+ LGL leukemia (patient no.)  
 1  96 44  80  90  
 2  78  30  62  43  
 3  85 74  85  ND  
 4  95  65  84  44 
 5  95  52  93  90  
 6  78  33  77  79 
 7  84  76  84  35  
 8 96  15  72 80  
 9  91  41  82  50  
 10 87  12 64  89  
 11  82  38  63  88  
Mean ± SD 88 ± 7   44 ± 22  77 ± 10 69 ± 23 
Samples Phenotype (%)
CD95CD57 CD57/CD95*CD95L
PBMC  35 ± 11 6 ± 2  32 ± 12  2 ± 1  
PBMC post-PHA/IL-2 94 ± 3   9 ± 2  90 ± 3   42 ± 5  
CD3+ LGL leukemia (patient no.)  
 1  96 44  80  90  
 2  78  30  62  43  
 3  85 74  85  ND  
 4  95  65  84  44 
 5  95  52  93  90  
 6  78  33  77  79 
 7  84  76  84  35  
 8 96  15  72 80  
 9  91  41  82  50  
 10 87  12 64  89  
 11  82  38  63  88  
Mean ± SD 88 ± 7   44 ± 22  77 ± 10 69 ± 23 

Abbreviations: PBMC, peripheral blood mononuclear cells from normal controls, n = 6; ND, not determined.

*

Percentage of CD57+ cells expressing CD95 is indicated.

Sixty-one percent of the cells were CD16+.

Thirty-eight percent of the cells were CD56+.

or Create an Account

Close Modal
Close Modal