Table 4. Adverse Events . Grades 3/4... | American Society of Hematology

Table 4.

Adverse Events

	Grades 3/4 Adverse Events	All Events Related to BTI-322
	Grades 3/4 Adverse Events	All Related	Occurred With Dose 1	Occurred With Doses 2-10
Total no. of events^4-150	156	44	39	2
Body as a whole	13	7^4-151	7	0
Cardiovascular	2	6^‡	6	1
Digestive	10	5^4-153	5	1
Endocrine	0	0	0	0
Heme/lymphatic	12	0	0	0
Metabolic/nutritional	9	0	0	0
Musculoskeletal	1	0	0	0
Nervous system	4	1^4-155	1	0
Repiratory system	6	6^4-154	6	0
Cutaneous	3	1	1	0
Special senses	0	0	0	0
Urogenital	8	0	0	0
Patients with ≥1 event	20	11	10	1

	Grades 3/4 Adverse Events	All Events Related to BTI-322
	Grades 3/4 Adverse Events	All Related	Occurred With Dose 1	Occurred With Doses 2-10
Total no. of events^4-150	156	44	39	2
Body as a whole	13	7^4-151	7	0
Cardiovascular	2	6^‡	6	1
Digestive	10	5^4-153	5	1
Endocrine	0	0	0	0
Heme/lymphatic	12	0	0	0
Metabolic/nutritional	9	0	0	0
Musculoskeletal	1	0	0	0
Nervous system	4	1^4-155	1	0
Repiratory system	6	6^4-154	6	0
Cutaneous	3	1	1	0
Special senses	0	0	0	0
Urogenital	8	0	0	0
Patients with ≥1 event	20	11	10	1

This row reports the number of adverse events. Remainder of table reports numbers of patients in each category.

Represents chills, fever, pruritus, flushing, pain.

Represents tachycardia, hypertension, hypotension, chest tightness.

Represents nausea, vomiting, diarrhea, retching.

Represents muscle cramps.

Represents dyspnea, shortness of breath, hypoxia, wheezing.