Clinical Characteristics of Study Patients
| Characteristics . | . |
|---|---|
| No. of patients | 185 |
| Age (yr) | |
| Range | 18-87 |
| Median | 54 |
| Hemoglobin (g/dL) | |
| Range | 2.8-14.4 |
| Median | 8.6 |
| White blood cell count (×109/L) | |
| Range | 0.3-233 |
| Median | 17.9 |
| Platelets (×109/L) | |
| Range | 1-835 |
| Median | 45 |
| % Bone marrow blasts | |
| Range | 0-99 |
| Median | 58 |
| % Peripheral blood blasts | |
| Range | 0-99 |
| Median | 39 |
| FAB category (no. of patients) | |
| M0 | 11 |
| M1 | 50 |
| M2 | 35 |
| M3 | 17 |
| M4 | 39 |
| M5 | 11 |
| M6 | 6 |
| M7 | 2 |
| Unclassified | 14 |
| Cytogenetic abnormality (no. of patients) | |
| Inversion 16 | 13 |
| t(8;21) | 8 |
| t(15;17) | 14 |
| Diploid | 59 |
| Insufficient metaphases | 9 |
| Miscellaneous | 26 |
| Trisomy 8 | 11 |
| −5, −7 | 37 |
| 11q | 5 |
| t(9;22) | 3 |
| Antecedent hematologic disorder (no. of patients) | 34 |
| Characteristics . | . |
|---|---|
| No. of patients | 185 |
| Age (yr) | |
| Range | 18-87 |
| Median | 54 |
| Hemoglobin (g/dL) | |
| Range | 2.8-14.4 |
| Median | 8.6 |
| White blood cell count (×109/L) | |
| Range | 0.3-233 |
| Median | 17.9 |
| Platelets (×109/L) | |
| Range | 1-835 |
| Median | 45 |
| % Bone marrow blasts | |
| Range | 0-99 |
| Median | 58 |
| % Peripheral blood blasts | |
| Range | 0-99 |
| Median | 39 |
| FAB category (no. of patients) | |
| M0 | 11 |
| M1 | 50 |
| M2 | 35 |
| M3 | 17 |
| M4 | 39 |
| M5 | 11 |
| M6 | 6 |
| M7 | 2 |
| Unclassified | 14 |
| Cytogenetic abnormality (no. of patients) | |
| Inversion 16 | 13 |
| t(8;21) | 8 |
| t(15;17) | 14 |
| Diploid | 59 |
| Insufficient metaphases | 9 |
| Miscellaneous | 26 |
| Trisomy 8 | 11 |
| −5, −7 | 37 |
| 11q | 5 |
| t(9;22) | 3 |
| Antecedent hematologic disorder (no. of patients) | 34 |
The median follow-up of patients alive on study is 123 weeks.