Detection of BCR-ABL Transcripts in Primary Normal Leukocytes and in Cell Lines: Summary of Results
| Source of Cells . | Characteristics . | No. Positive/ No. Tested . | |
|---|---|---|---|
| p210 BCR-ABL . | p190 BCR-ABL . | ||
| Normal adults (PB WBC) | 7 male and 9 female, age = 33 ± 7 yr | 4/15 (27%) | 11/16 (69%) |
| Hematopoietic cell lines (Ph−) | AML, histiocytic NHL, T-ALL, B-PLL, normal EBV-transformed B cells | 3/7 (43%) | 7/7 (100%) |
| Murine fibroblast line | NIH-3T3 (4 batches) | 0/2 (0%) | 0/4 (0%) |
| Source of Cells . | Characteristics . | No. Positive/ No. Tested . | |
|---|---|---|---|
| p210 BCR-ABL . | p190 BCR-ABL . | ||
| Normal adults (PB WBC) | 7 male and 9 female, age = 33 ± 7 yr | 4/15 (27%) | 11/16 (69%) |
| Hematopoietic cell lines (Ph−) | AML, histiocytic NHL, T-ALL, B-PLL, normal EBV-transformed B cells | 3/7 (43%) | 7/7 (100%) |
| Murine fibroblast line | NIH-3T3 (4 batches) | 0/2 (0%) | 0/4 (0%) |
Abbreviations: PB WBCs, peripheral blood white blood cells; AML, acute myeloblastic leukemia; ALL, acute lymphoblastic leukemia; PLL, prolymphocytic leukemia.