Table 1.

Granulocyte Functions: Patient (Before and After BMT), Donor, and Normal Control

Patient Heterozygous Donor Normal Control
Before BMT After BMT
NBT test (% positivity)  
 PMA  0  55.00  55.00 99.00  
 OPZ  0  62.00  60.00  100.00 
Cytochrome-b spectrum (pmol/106 granulocytes)  5.90  4.70  6.50  
Superoxide production (nmol/106 granulocytes/min)  
 PMA  0  10.74 5.86  14.65  
 fMLP  0  12.46  9.34 17.76 
Patient Heterozygous Donor Normal Control
Before BMT After BMT
NBT test (% positivity)  
 PMA  0  55.00  55.00 99.00  
 OPZ  0  62.00  60.00  100.00 
Cytochrome-b spectrum (pmol/106 granulocytes)  5.90  4.70  6.50  
Superoxide production (nmol/106 granulocytes/min)  
 PMA  0  10.74 5.86  14.65  
 fMLP  0  12.46  9.34 17.76 

Abbreviations: BMT, bone-marrow transplantation; NBT, nitroblue tetrazolium; PMA, phorbol-myristate-acetate; OPZ, opsonized zymosan particles; fMLP, N-formyl-methionyl-leucyl-phenylalanine.