Table 1.

Phenotype of Chimeric Human Cells Harvested From NOD/SCID Mice Transplanted With G0CD34+Cells

% Engrafted Human Cells With Indicated Phenotype
% CD45+Cells % CD34+
CD34+CD19+CD33+CD15+CD38CD19+CD33+
Mean ± SEM  19.9 ± 3.1  55.7 ± 5.1 34.2 ± 5.1  35.0 ± 5.2  2.1 ± 0.6 64.6 ± 2.3  18.2 ± 2.4  
Range  11.7-29.5 34.3-75.9  17.2-54.6  16.7-53.1  0.5-4.8  54.1-74.0 12.1-27.9 
% Engrafted Human Cells With Indicated Phenotype
% CD45+Cells % CD34+
CD34+CD19+CD33+CD15+CD38CD19+CD33+
Mean ± SEM  19.9 ± 3.1  55.7 ± 5.1 34.2 ± 5.1  35.0 ± 5.2  2.1 ± 0.6 64.6 ± 2.3  18.2 ± 2.4  
Range  11.7-29.5 34.3-75.9  17.2-54.6  16.7-53.1  0.5-4.8  54.1-74.0 12.1-27.9 

The phenotypic profile of BM cells harvested from NOD/SCID mice transplanted 6 weeks previously with G0CD34+cells was determined by FACScan analysis. Cells were stained with antihuman CD45-FITC or antihuman CD34-FITC and PE-conjugated antihuman MoAbs of indicated specificity. Data shown are from three experiments (n = 2 or 3 animals per experiment).

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