Clinical Findings, Prognostic Staging, and MRI Pattern of the Patients With Myelofibrosis
| Patient No. . | Age/ Sex . | Diagnosis . | Hb (g/dL) . | Platelet Count (×109/μL) . | Myeloid Precursors (%) . | LDH (IU/L) . | Histopathologic Staging* . | Prognostic Staging-151 . | MRI Pattern . |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 66/F | Secondary | 5.3 | 27 | 3 | 1,209 | 2 | 2 | 1A |
| 2 | 64/F | Secondary | 7.8 | 56 | 15 | 2,123 | 3 | 3 | 1A |
| 3 | 30/F | Primary | 10.9 | 488 | 6 | 519 | 1 | 1 | 1A |
| 4 | 37/M | Primary | 8.7 | 490 | 23 | 1,617 | 3 | 3 | 2 |
| 5 | 66/M | Primary | 7.9 | 242 | 14 | 1,366 | 1 | 3 | 2 |
| 6 | 59/M | Primary | 11.6 | 320 | 7 | 920 | 1 | 1 | 1A |
| 7 | 58/M | Primary | 9.3 | 74 | 29 | 980 | 1 | 3 | 1B |
| 8 | 61/M | Primary | 12.8 | 310 | 4 | 853 | 1 | 1 | 1B |
| 9 | 34/F | Primary | 8.4 | 230 | 17 | 1,450 | 2 | 3 | 2 |
| 10 | 57/M | Primary | 5.3 | 5 | 34 | 2,300 | 3 | 3 | 2 |
| 11 | 52/M | Primary | 12.6 | 240 | 8 | 736 | 1 | 1 | 1A |
| 12 | 66/M | Primary | 7.5 | 698 | 10 | 528 | 2 | 2 | 1B |
| 13 | 48/F | Primary | 10.3 | 204 | 24 | 1,785 | 2 | 3 | 1B |
| Patient No. . | Age/ Sex . | Diagnosis . | Hb (g/dL) . | Platelet Count (×109/μL) . | Myeloid Precursors (%) . | LDH (IU/L) . | Histopathologic Staging* . | Prognostic Staging-151 . | MRI Pattern . |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 66/F | Secondary | 5.3 | 27 | 3 | 1,209 | 2 | 2 | 1A |
| 2 | 64/F | Secondary | 7.8 | 56 | 15 | 2,123 | 3 | 3 | 1A |
| 3 | 30/F | Primary | 10.9 | 488 | 6 | 519 | 1 | 1 | 1A |
| 4 | 37/M | Primary | 8.7 | 490 | 23 | 1,617 | 3 | 3 | 2 |
| 5 | 66/M | Primary | 7.9 | 242 | 14 | 1,366 | 1 | 3 | 2 |
| 6 | 59/M | Primary | 11.6 | 320 | 7 | 920 | 1 | 1 | 1A |
| 7 | 58/M | Primary | 9.3 | 74 | 29 | 980 | 1 | 3 | 1B |
| 8 | 61/M | Primary | 12.8 | 310 | 4 | 853 | 1 | 1 | 1B |
| 9 | 34/F | Primary | 8.4 | 230 | 17 | 1,450 | 2 | 3 | 2 |
| 10 | 57/M | Primary | 5.3 | 5 | 34 | 2,300 | 3 | 3 | 2 |
| 11 | 52/M | Primary | 12.6 | 240 | 8 | 736 | 1 | 1 | 1A |
| 12 | 66/M | Primary | 7.5 | 698 | 10 | 528 | 2 | 2 | 1B |
| 13 | 48/F | Primary | 10.3 | 204 | 24 | 1,785 | 2 | 3 | 1B |
*Pathologic staging of myelofibrosis: 1, a cellular phase with panmyelosis, megakaryocytic and erytroid proliferation, and minimal increase in reticulin fibers; 2, myelofibrosis, with only 30% of the marrow space showing hematopoietic tissue; 3, myelofibrosis with osteosclerosis, wide-spread fibrosis and a minimal amount of hematopoietic tissue.
Clinical prognostic staging2: 1, good-risk, with Hb >10 g/dL and percentage of myeloid precursors <10%; 2, intermediate-risk, with Hb <10 g/dL and percentage of myeloid precursors <10%; 3, high-risk, with >10% of myeloid precursors, independent of Hb level.