Contribution of Endogenous BALB/c Retrovirus to Leukemic Transformation
| Plasma/Supernatant . | Leukemia . | Viremia/Wild-Type Virus . |
|---|---|---|
| MSCV-FL 196 | Yes | + |
| SPL196 (3°, cultured) | Yes | + |
| MSCV-FL 197 | Yes | + |
| MSCV-FL 198 | No | − |
| MSCV-FL 198 (2°) | Yes | + |
| SPL198 (2°, cultured) | Yes | + |
| MSCV-FL 199 | Yes | + |
| MSCV-FL 200 | No | − |
| MSCV-FL 201 | No | − |
| MSCV-FL 201 (2°) | Yes | − |
| MSCV-FL 202 | No | + |
| SPL203 (3°, cultured) | Yes | − |
| SPL204 (2°, cultured) | Yes | − |
| SPL204 (3°, cultured) | Yes | − |
| MSCV-FL 208 (2°) | Yes | + |
| MSCV-FL 211 (2°) | Yes | + |
| MSCV 206 | No | − |
| MSCV 207 | No | − |
| Plasma/Supernatant . | Leukemia . | Viremia/Wild-Type Virus . |
|---|---|---|
| MSCV-FL 196 | Yes | + |
| SPL196 (3°, cultured) | Yes | + |
| MSCV-FL 197 | Yes | + |
| MSCV-FL 198 | No | − |
| MSCV-FL 198 (2°) | Yes | + |
| SPL198 (2°, cultured) | Yes | + |
| MSCV-FL 199 | Yes | + |
| MSCV-FL 200 | No | − |
| MSCV-FL 201 | No | − |
| MSCV-FL 201 (2°) | Yes | − |
| MSCV-FL 202 | No | + |
| SPL203 (3°, cultured) | Yes | − |
| SPL204 (2°, cultured) | Yes | − |
| SPL204 (3°, cultured) | Yes | − |
| MSCV-FL 208 (2°) | Yes | + |
| MSCV-FL 211 (2°) | Yes | + |
| MSCV 206 | No | − |
| MSCV 207 | No | − |
Plasma from primary and secondary MSCV-FL transplant recipients or supernatants from cultured leukemic spleen (SPL) cells were assayed for wild-type viruses by using a marker vector mobilization assay as described in Materials and Methods.