Table 2. The Ratio of Bcl-2 low and... | American Society of Hematology

Table 2.

The Ratio of Bcl-2^low and Bcl-2^high Calculated for CD34⁺ Hematopoietic Precursors (CD38^−/low and HLA-DR^−/low) and Compared With the Ratio for More Mature Cells (CD38³⁺ and HLA-DR³⁺) in MPB, CB, and BM

Sample	No.	CD38^−/low	CD38³⁺	HLA-DR^−/low	HLA-DR³⁺	P Value
MPB	22	1.2 ± 0.85	0.42 ± 0.25			.0001
	12			0.61 ± 0.3	0.3 ± 0.17	.003
CB	12	0.98 ± 0.43	0.31 ± 0.22			.0001
	6			0.74 ± 0.45	0.23 ± 0.15	.038
BM	8	0.67 ± 0.50	0.16 ± 0.19			.02
	3			0.56 ± 0.08	0.15 ± 0.12	.07

Sample	No.	CD38^−/low	CD38³⁺	HLA-DR^−/low	HLA-DR³⁺	P Value
MPB	22	1.2 ± 0.85	0.42 ± 0.25			.0001
	12			0.61 ± 0.3	0.3 ± 0.17	.003
CB	12	0.98 ± 0.43	0.31 ± 0.22			.0001
	6			0.74 ± 0.45	0.23 ± 0.15	.038
BM	8	0.67 ± 0.50	0.16 ± 0.19			.02
	3			0.56 ± 0.08	0.15 ± 0.12	.07

Two populations were shown by anti–bcl-2 staining. The calculated ratio is based on the percentage of positive cells expressing bcl-2 in each area (bcl-2^low and bcl-2^high). Significant P values were obtained from all cell sources between the ratio for bcl-2^low and bcl-2^high in primitive hematopoietic cells and more mature cells.

View Large

This Feature Is Available To Subscribers Only