CD34+ and GM-CFC Content in Fresh BM Harvested Before and After Administration of 6 Cycles of FAC Chemotherapy
| BB10010 (μg/kg) . | GM-CFC . | CD34+ . | ||
|---|---|---|---|---|
| Pretreatment . | Posttreatment . | Pretreatment . | Posttreatment . | |
| 0 (n = 4) | 25 ± 10 | 18 ± 4 | 0.7 ± 0.2 | 2.7 ± 0.83-150 |
| 30 (n = 7) | 36 ± 16 | 21 ± 9 | 1.1 ± 0.2 | 1.2 ± 0.2 |
| 100 (n = 5) | 23 ± 21 | 26 ± 13 | 0.8 ± 0.2 | 0.8 ± 0.2 |
| BB10010 (μg/kg) . | GM-CFC . | CD34+ . | ||
|---|---|---|---|---|
| Pretreatment . | Posttreatment . | Pretreatment . | Posttreatment . | |
| 0 (n = 4) | 25 ± 10 | 18 ± 4 | 0.7 ± 0.2 | 2.7 ± 0.83-150 |
| 30 (n = 7) | 36 ± 16 | 21 ± 9 | 1.1 ± 0.2 | 1.2 ± 0.2 |
| 100 (n = 5) | 23 ± 21 | 26 ± 13 | 0.8 ± 0.2 | 0.8 ± 0.2 |
Data are shown as mean ± SE. Values represent absolute CD34+ cells (×10−5) per 107methylcellulose separated BM cells. GM-CFC data are colony counts per 105 BMMNC.
P (v pretreatment level) = 0.06; not significant.