Effect of IL-1Ra on Surface Expression of CD54 and CD106 on HUVECs
| Conditions . | Thrombin . | Thrombin + IL-1Ra . | IL-1β . | IL-1β + IL-1Ra . |
|---|---|---|---|---|
| CD54 | 34 ± 1.5 | 30 ± 4.5 | 38 ± 1.5 | 3.6 ± 24-150 |
| CD106 | 37 ± 9 | 33 ± 9.5 | 55 ± 6 | 10.5 ± 24-150 |
| Conditions . | Thrombin . | Thrombin + IL-1Ra . | IL-1β . | IL-1β + IL-1Ra . |
|---|---|---|---|---|
| CD54 | 34 ± 1.5 | 30 ± 4.5 | 38 ± 1.5 | 3.6 ± 24-150 |
| CD106 | 37 ± 9 | 33 ± 9.5 | 55 ± 6 | 10.5 ± 24-150 |
HUVECs were cultured for 6 hours in the presence of thrombin (8 U/mL) or IL-1β (50 pg/mL) with or without IL-1Ra (10 μg/mL). After cell trypsinization, CD54 and CD106 expression was studied by FACS analysis (percentage of positive cells).
P < .03 when compared with respective control (n = 3).