A Comparative Review of Studies on Clinical Significance of MyAg Coexpression in ALL
| Author, Year . | No. of Cases . | MyAg+ALL No. (%) . | MyAg Used . | % IFI . | Confirmation of Coexpression . | Correlation With EFS . |
|---|---|---|---|---|---|---|
| Pui et al, 1990 | 372 | 61 (6.4) | CD11b, 13, 14 CD15, 33, 36 | 25 | DF | No (FU, 36 mo) |
| Wiersma et al, 1991 | 236 | 52 (22) | CD13, 33, 14 | 30 | OVL DF | Yes (FU, 40 mo) |
| Borowitz et al, 1991 | 1141 | (7) (15) | CD13, 33 CD13, 33 | 30 20 | 30% OVL ND | No No |
| Pui et al, 1991 | 410 | 25 (6.1) | CD11b, 13, 14 CD15, 33, 36 | 20 2 MyAg+ | ND | |
| Fink et al, 1993 | 206 | 24 (11) | CD13, 33, 65, 15 14, 11b, GA, 41 | OVL | Yes (median FU, 44 mo) | |
| Ludwig et al, 1994 | 736 | 50 (7) | CD13, 33, 65 | 20 | DF | ND |
| Reiter et al, 1994 | 975 | 51 (5) | CD13, 33, 65 | 20 | 20% OVL | No |
| Uckun et al, 1997 | 1557 | 260 (16.6) | CD13, 33 | 30 | No (FU, 73 mo) |
| Author, Year . | No. of Cases . | MyAg+ALL No. (%) . | MyAg Used . | % IFI . | Confirmation of Coexpression . | Correlation With EFS . |
|---|---|---|---|---|---|---|
| Pui et al, 1990 | 372 | 61 (6.4) | CD11b, 13, 14 CD15, 33, 36 | 25 | DF | No (FU, 36 mo) |
| Wiersma et al, 1991 | 236 | 52 (22) | CD13, 33, 14 | 30 | OVL DF | Yes (FU, 40 mo) |
| Borowitz et al, 1991 | 1141 | (7) (15) | CD13, 33 CD13, 33 | 30 20 | 30% OVL ND | No No |
| Pui et al, 1991 | 410 | 25 (6.1) | CD11b, 13, 14 CD15, 33, 36 | 20 2 MyAg+ | ND | |
| Fink et al, 1993 | 206 | 24 (11) | CD13, 33, 65, 15 14, 11b, GA, 41 | OVL | Yes (median FU, 44 mo) | |
| Ludwig et al, 1994 | 736 | 50 (7) | CD13, 33, 65 | 20 | DF | ND |
| Reiter et al, 1994 | 975 | 51 (5) | CD13, 33, 65 | 20 | 20% OVL | No |
| Uckun et al, 1997 | 1557 | 260 (16.6) | CD13, 33 | 30 | No (FU, 73 mo) |
Only series analyzed by flow cytometry have been shown.
Abbreviations: % IFI, percentage of cells positive by single fluorescence analysis; DF, double fluorescence staining; OVL, overlapping of percentages of positive cells; FU, follow-up; mo, months; ND, not done; GA, glycophorin A.