Cytological Analysis of Hematopoietic Colonies
| Cell Type . | WT (% ± SD) . | d716 (% ± SD . | GEpoR (% ± SD) . |
|---|---|---|---|
| Late myeloid | 29.3 ± 8.0 | 26.9 ± 8.5 | 36.5 ± 8.8 |
| Early myeloid | 29.1 ± 11.2 | 24.6 ± 4.5 | 30.8 ± 3.9 |
| Macrophage | 17.4 ± 8.0 | 31.9 ± 9.6 | 25.0 ± 10.0 |
| Erythroblast | 2.5 ± 1.8 | 1.9 ± 1.8 | 1.4 ± 1.1 |
| Basophil | 22.6 ± 8.3 | 14.9 ± 2.1 | 5.1 ± 3.0-150 |
| Cell Type . | WT (% ± SD) . | d716 (% ± SD . | GEpoR (% ± SD) . |
|---|---|---|---|
| Late myeloid | 29.3 ± 8.0 | 26.9 ± 8.5 | 36.5 ± 8.8 |
| Early myeloid | 29.1 ± 11.2 | 24.6 ± 4.5 | 30.8 ± 3.9 |
| Macrophage | 17.4 ± 8.0 | 31.9 ± 9.6 | 25.0 ± 10.0 |
| Erythroblast | 2.5 ± 1.8 | 1.9 ± 1.8 | 1.4 ± 1.1 |
| Basophil | 22.6 ± 8.3 | 14.9 ± 2.1 | 5.1 ± 3.0-150 |
Three hundred count manual leukocyte differentials were performed on cells isolated from methylcellulose cultures after 10 days of G-CSF stimulation. Late myeloid cells included polymorphonuclear, ring, and band neutrophils as well as neutrophilic metamyelocytes. Early myeloid cells included myelocytes, promyelocytes, and myeloblasts. Data represent the mean ± SD of four independent experiments.
P < .05 compared with WT.